Evidence map›Paper›PMID 30511464›Full record

ArticleJournal of biophotonics2019

Photoacoustic and fluorescent effects in multilayer plasmon-dye interfaces.

Marina V Novoselova, Daniil N Bratashov, Mustafa Sarimollaoglu, Dmitry A Nedosekin, Walter Harrington, Alex Watts, Mikyung Han, Boris N Khlebtsov, Ekaterina I Galanzha, Dmitry A Gorin and 1 more

Abstract read
In one paragraph

Article in Journal of biophotonics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Marina V NovoselovaBiophotonics Laboratory, Skoltech Center for Photonics and Quantum Materials, Skolkovo Institute of Science and Technology, Moscow, Russia.ORCID 0000-0001-6268-5058
Daniil N BratashovBiomedical Photoacoustics Laboratory, Saratov State University, Saratov, Russia.
Mustafa SarimollaogluDepartment of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Dmitry A NedosekinDepartment of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Walter HarringtonDepartment of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Alex WattsDepartment of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Mikyung HanDepartment of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, Little Rock, Arkansas.
Boris N KhlebtsovBiomedical Photoacoustics Laboratory, Saratov State University, Saratov, Russia.
Ekaterina I GalanzhaBiomedical Photoacoustics Laboratory, Saratov State University, Saratov, Russia.
Dmitry A GorinBiophotonics Laboratory, Skoltech Center for Photonics and Quantum Materials, Skolkovo Institute of Science and Technology, Moscow, Russia.ORCID 0000-0001-8760-615X
Vladimir P ZharovBiomedical Photoacoustics Laboratory, Saratov State University, Saratov, Russia.

Funding

In vivo real-time detection of circulating melanoma cellsR01CA131164 · NCI · UNIV OF ARKANSAS FOR MED SCIS · PI SUEN, JAMES · 2009 to 2019
$3.1M
Government of the Russian Federation 14.Z50.31.0044NCI NIH HHS R01 CA131164
6 · The paper itself

Abstract

Progress in understanding the cell biology and diseases depends on advanced imaging and labeling techniques. Here, we address this demand by exploring novel multilayered nanocomposites (MNCs) with plasmonic nanoparticles and absorbing dyes in thin nonabsorbing shells as supercontrast multimodal photoacoustic (PA) and fluorescent agents in the near-infrared range. The proof of concept was performed with gold nanorods (GNRs) and indocyanine green (ICG) dispersed in a matrix of biodegradable polymers. We demonstrated synergetic PA effects in MNCs with the gold-ICG interface that could not be achieved with ICG and GNRs alone. We also observed ultrasharp PA and emission peaks that could be associated with nonlinear PA and spaser effects, respectively. Low-toxicity multimodal MNCs with unique plasmonic, thermal and acoustic properties have the potential to make a breakthrough in PA flow cytometry and near-infrared spasers in vivo by using the synergetic interaction of plasmonic modes with a nearby absorbing medium.

Indexed as

Photoacoustic TechniquesAnimalsFluorescent DyesGoldIndocyanine GreenMiceNanocompositesNanotubesFluorescent DyesGoldIndocyanine Greenbiocompatible polymersfluorescencefluorescence quenchinggold nanorodsindocyanine greenin vivo flow cytometrymultilayer compositephotoacoustic effect

Identifiers

PMID30511464
PMCPMC9241577

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.