Trial reportSurgical endoscopy2019
Comparison of inflammatory stress response between laparoscopic and open approach for pediatric inguinal hernia repair in children.
Trial report in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.
- Laparoscopic percutaneous extraperitoneal closure versus open repair in pediatric inguinal hernia: a systematic review and meta-analysis of comparative outcomes.Hernia : the journal of hernias and abdominal wall surgery · 2026Pooled it
- Effects of deep neuromuscular block on surgical pleth index-guided remifentanil administration in laparoscopic herniorrhaphy: a prospective randomized trial.Scientific reports · 2022Trial
- Postoperative C-Reactive Protein as a Marker of the Early Inflammatory Response in Robotic Versus Laparoscopic Minimally Invasive Surgery for Endometrial Cancer: A Propensity Score-Matched Analysis.Journal of clinical medicine · 2026Article
- Comparing Surgical Stress in Children Undergoing Open and Laparoscopic Inguinal Hernioplasty-A Single Center's Prospective Study Results.Children (Basel, Switzerland) · 2025Article
- Comparison of Percutaneous Internal Ring Suturing (PIRS) versus Open Ligation of the Patent Processus Vaginalis for the Treatment of Communicating Pediatric Hydrocele.Children (Basel, Switzerland) · 2024Article
- Is Laryngeal Mask a Good Alternative in Children Undergoing Laparoscopic Inguinal Hernia Repair with Percutaneous Internal Ring Suturing Under and Over Two Years Old?Turkish journal of anaesthesiology and reanimation · 2023Article
- Studying the surgical stress in open and laparoscopic treatment of inguinal hernia in children.Pediatric investigation · 2023Article
- Measuring Children's Stress via Saliva in Surgical and Endoscopic Procedures and Its Measurement Intention in the Community: Reality-Future Prospects.Children (Basel, Switzerland) · 2023Article
- Comparison of laparoscope-assisted single-needle laparoscopic percutaneous extraperitoneal closure versus open repair for pediatric inguinal hernia.BMC surgery · 2022Article
- Comparison of Surgical Outcomes of Laparoscopic Glue and Laparoscopic Suture Hernioplasty in Pediatric Female Inguinal Hernia.Children (Basel, Switzerland) · 2022Article
- Laparoscopic Hernia Repair with the Extraperitoneal Approach versus Open Hernia Repair in Pediatric Inguinal Hernia: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2022Review
- Early kinetics of calprotectin in plasma following inguinal hernia surgery.Innate immunity · 2022Article
- Application Effect of Combining Image-Text Communication-Based Healthcare Education with Shifting of Attention on Child Patients Undergoing Inguinal Hernia Repair under General Anesthesia.Contrast media & molecular imaging · 2022Article
- Comparison of Recurrence and Complication Rates Following Laparoscopic Inguinal Hernia Repair among Preterm versus Full-Term Newborns: A Systematic Review and Meta-Analysis.Children (Basel, Switzerland) · 2021Review
- Learning Curve for Laparoscopic Repair of Pediatric Inguinal Hernia Using Percutaneous Internal Ring Suturing.Children (Basel, Switzerland) · 2021Article
- Short-Periods of Pre-Warming in Laparoscopic Surgery. A Non-Randomized Clinical Trial Evaluating Current Clinical Practice.Journal of clinical medicine · 2021Article
- Modified percutaneous internal ring suturing with peritoneal injury in children: matched comparison to open hernia repair.Surgical endoscopy · 2021Article
- Single-site laparoscopic percutaneous extraperitoneal closure (SLPEC) of hernia sac high ligation using an ordinary taper needle: a novel technique for pediatric inguinal hernia.Hernia : the journal of hernias and abdominal wall surgery · 2020Article
- A rare content of congenital inguinal hernia: a case report of splenogonadal fusion.BMC pediatrics · 2019Article
- Laparoscopic versus open inguinal hernia repair in children: A systematic review.Journal of minimal access surgeryReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to compare inflammatory stress response between laparoscopic percutaneous inguinal ring suturing (PIRS) and open modified Marcy technique for pediatric inguinal hernia repair.
methodsFrom May 2017 to April 2018, 32 male children with median age of 4.5 years undergoing inguinal hernia repair were included in randomized controlled trial. The patients were divided in two groups, by using random number generator, depending on surgical approach. The blood was tested in three time frames for white blood cells count (WBC), C-reactive protein (CRP), Interleukin-6 (IL-6), and tumor necrosis factor alpha (TNF-α).
resultsSignificant increase in concentration for all inflammatory biomarkers, that occur over time, has been found (p < 0.001 for all). Additionally, it was also found that the type of surgery significantly influenced the level of WBC, CRP, and IL-6 with Marcy showing a higher level of inflammatory response (WBC 11.4 ± 3.1 × 10
conclusionsUse of laparoscopic (PIRS) technique in children shows significantly lower surgical stress in comparison to open hernia repair.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.