ArticleEJNMMI physics2018
Fast quantitative reconstruction with focusing collimators for liver SPECT.
Article in EJNMMI physics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Physics-Guided Deep Scatter Estimation by Weak Supervision for Quantitative SPECT.IEEE transactions on medical imaging · 2023Article
- A compact and mobile hybrid C-arm scanner for simultaneous nuclear and fluoroscopic image guidance.European radiology · 2022Article
- Advanced Monte Carlo simulations of emission tomography imaging systems with GATE.Physics in medicine and biology · 2021Review
- Technical Note: Nuclear imaging with an x-ray flat panel detector: A proof-of-concept study.Medical physics · 2020Article
- Monte Carlo-based scatter correction for the SMARTZOOM collimator.EJNMMI physics · 2020Article
- Adaptive scan duration in SPECT: Evaluation for radioembolization.Medical physics · 2020Article
- Respiratory motion compensation in interventional liver SPECT using simultaneous fluoroscopic and nuclear imaging.Medical physics · 2019Article
- Accelerated SPECT image reconstruction with FBP and an image enhancement convolutional neural network.EJNMMI physics · 2019Article
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Authors and funding
5 authors.
Funding
Abstract
backgroundGeneration of a SPECT scan during procedure may aid in the optimization of treatments as liver radioembolization by offering image-guided dosimetry. This, however, requires both shortened acquisition times and fast quantitative reconstruction. Focusing collimators increase sensitivity and thus may speed up imaging. Monte Carlo-based iterative reconstruction has shown to provide quantitative results for parallel hole collimators but may be slow. The purpose of this work is to develop fast Monte Carlo-based reconstruction for focusing collimators and to evaluate the impact of reconstruction and collimator choice on quantitative accuracy of liver dosimetry by means of simulations.
resultsThe developed fast Monte Carlo simulator was found to accurately generate projections compared to a full Monte Carlo simulation, providing projections in several seconds instead of several days. Monte Carlo-based scatter correction was superior to other scatter correction methods in describing recovered activity and reached similar noise levels as dual-energy window scatter correction. Although truncation artifacts were present in the cone beam collimator (50 cm), the region inside the field of view (FOV) could be reconstructed without loss of accuracy. Provided the object to image is inside the FOV, the focusing collimator with 50 cm focal distance could retrieve the same noise levels as a parallel hole collimator in 68% of the total scanning time, the multifocal collimator in 73% of the time, and the 100-cm focal distance collimator in 84% of the time.
conclusionFocusing collimators combined with Monte Carlo-based reconstruction have the ability to enable quantitative imaging of the FOV in a significantly shorter timeframe. The proposed approach to the forward projector will additionally make it possible to reconstruct within minutes. These are crucial steps in moving toward real-time dosimetry during interventions.
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