Evidence map›Paper›PMID 30511106›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2019

Amide proton transfer MRI detects early changes in nasopharyngeal carcinoma: providing a potential imaging marker for treatment response.

Sahrish Qamar, Ann D King, Qi-Yong Ai, Benjamin King Hong Law, Janet S M Chan, Darren M C Poon, Macy Tong, Frankie Kwok Fai Mo, Weitian Chen, Kunwar S Bhatia and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 3 countries.

Sahrish QamarDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China.
Ann D KingDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China. king2015@cuhk.edu.hk.ORCID http://orcid.org/0000-0002-5280-8349
Qi-Yong AiDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China.
Benjamin King Hong LawDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China.
Janet S M ChanDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China.
Darren M C PoonDepartment of Clinical Oncology, State Key Laboratory Translational Oncology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong S.A.R., China.
Macy TongDepartment of Clinical Oncology, State Key Laboratory Translational Oncology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong S.A.R., China.
Frankie Kwok Fai MoDepartment of Clinical Oncology, State Key Laboratory Translational Oncology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong S.A.R., China.
Weitian ChenDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China.
Kunwar S BhatiaImaging Department, St Mary's Hospital, Imperial College Healthcare, National Health Service Trust, London, UK.
Anil T AhujaDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China.
Brigette B Y MaDepartment of Clinical Oncology, State Key Laboratory Translational Oncology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong S.A.R., China.
David Ka-Wai YeungDepartment of Clinical Oncology, State Key Laboratory Translational Oncology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong S.A.R., China.
Yi-Xiang WangDepartment of Imaging and Interventional Radiology, Faculty of Medicine, The Chinese University of Hong Kong, Prince of Wales Hospital, 30-32 Ngan Shing Street, Shatin, New Territories, Hong Kong S.A.R., China.
Jing YuanMedical Physics and Research Department, Hong Kong Sanatorium & Hospital, Happy Valley, Hong Kong S.A.R., China.
Chinese University of Hong Kong · HKHong Kong Sanatorium and Hospital · HKNational Health Service · GB

Funding

Research Grants Council of Hong Kong CUHK141070/14 and SEG_CUHK02
6 · The paper itself

Abstract

purposeTo determine if treatment of nasopharyngeal carcinoma (NPC) induces early changes in amide proton transfer-weighted (APTw) magnetic resonance imaging (MRI), and to perform a preliminary evaluation of APTw imaging in response assessment.

methodsSixteen patients with NPC planned for treatment with radiotherapy and/or chemotherapy underwent APTw imaging of the primary tumour pre-treatment and 2-week intra-treatment. Difference in pre- and intra-treatment APT mean (APT

resultsAPT

conclusionAPT value changes can be detected in early intra-treatment. Intra-treatment %Δ APT

Indexed as

AdultAgedAmidesChemoradiotherapyFemaleHumansMagnetic Resonance ImagingMaleMiddle AgedNasopharyngeal CarcinomaNeoadjuvant TherapyProspective StudiesProtonsAmidesProtonsAmide proton transfer-weighted imagingChemical exchange saturation transferMagnetic resonance imagingNasopharyngeal carcinomaTreatment response

Identifiers

PMID30511106
OpenAlexW2903556980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.