Evidence map›Paper›PMID 30511050›Full record

ArticleProceedings of the ... ACM International Conference on Multimodal Interaction. ICMI (Conference)2018

Automated Affect Detection in Deep Brain Stimulation for Obsessive-Compulsive Disorder: A Pilot Study.

Jeffrey F Cohn, Michael S Okun, Laszlo A Jeni, Itir Onal Ertugrul, David Borton, Donald Malone, Wayne K Goodman

Abstract read
In one paragraph

Article in Proceedings of the ... ACM International Conference on Multimodal Interaction. ICMI (Conference), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Closed-loop neurostimulation for the treatment of psychiatric disorders.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2024
    Review
  3. Review
  4. Article
  5. Article
  6. Crossing Domains for AU Coding: Perspectives, Approaches, and Measures.IEEE transactions on biometrics, behavior, and identity science · 2020
    Article
  7. Article
  8. Article
  9. AFAR: A Deep Learning Based Tool for Automated Facial Affect Recognition.Proceedings of the ... International Conference on Automatic Face and Gesture Recognition. IEEE International Conference on Automatic Face & Gesture Recognition · 2019
    Article
  10. Cross-domain AU Detection: Domains, Learning Approaches, and Measures.Proceedings of the ... International Conference on Automatic Face and Gesture Recognition. IEEE International Conference on Automatic Face & Gesture Recognition · 2019
    Article
  11. Automated Affect Detection in Deep Brain Stimulation for Obsessive-Compulsive Disorder: A Pilot Study.Proceedings of the ... ACM International Conference on Multimodal Interaction. ICMI (Conference) · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jeffrey F CohnUniversity of Pittsburgh, Pittsburgh, PA.
Michael S OkunUniversity of Florida, Gainesville, Florida.
Laszlo A JeniCarnegie Mellon University, Pittsburgh, PA.
Itir Onal ErtugrulCarnegie Mellon University, Pittsburgh, PA.
David BortonBrown University, Providence, Rhode Island.
Donald MaloneCleveland Clinic, Cleveland, Ohio.
Wayne K GoodmanBaylor College of Medicine, Houston, Texas.

Funding

Measuring Automated Behavioral Observations & Vocal Expressions (ABOVE) while Recording from the BrainUH3NS100549 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI GOODMAN, WAYNE K · 2016 to 2022
$7.8M
Automatic Multimodal Affect Detection for Research and Clinical Use R01MH096951 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI COHN, JEFFREY F · 2012 to 2021
$5.6M
NIMH NIH HHS R01 MH096951NINDS NIH HHS UH3 NS100549
6 · The paper itself

Abstract

Automated measurement of affective behavior in psychopathology has been limited primarily to screening and diagnosis. While useful, clinicians more often are concerned with whether patients are improving in response to treatment. Are symptoms abating, is affect becoming more positive, are unanticipated side effects emerging? When treatment includes neural implants, need for objective, repeatable biometrics tied to neurophysiology becomes especially pressing. We used automated face analysis to assess treatment response to deep brain stimulation (DBS) in two patients with intractable obsessive-compulsive disorder (OCD). One was assessed intraoperatively following implantation and activation of the DBS device. The other was assessed three months post-implantation. Both were assessed during DBS on and o conditions. Positive and negative valence were quantified using a CNN trained on normative data of 160 non-OCD participants. Thus, a secondary goal was domain transfer of the classifiers. In both contexts, DBS-on resulted in marked positive affect. In response to DBS-off, affect flattened in both contexts and alternated with increased negative affect in the outpatient setting. Mean AUC for domain transfer was 0.87. These findings suggest that parametric variation of DBS is strongly related to affective behavior and may introduce vulnerability for negative affect in the event that DBS is discontinued.

Indexed as

Action unitsBehavioral dynamicsBody expressionDeep brain stimulationFacial expressionObsessive compulsive disorderSocial signal processing

Identifiers

PMID30511050
PMCPMC6271416

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.