Evidence map›Paper›PMID 30511038›Full record

ReviewBJS open2018

Systematic review of the stage of innovation of biological mesh for complex or contaminated abdominal wall closure.

S K Kamarajah, S J Chapman, J Glasbey, D Morton, N Smart, T Pinkney, A Bhangu

Abstract readReview
In one paragraph

Review in BJS open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  16. InvasiveCanadian journal of surgery. Journal canadien de chirurgie
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

S K KamarajahCollege of Medical and Dental Sciences University of Birmingham Birmingham UK.
S J ChapmanLeeds Institute of Biomedical and Clinical Sciences University of Leeds Leeds UK.ORCID https://orcid.org/0000-0003-2413-5690
J GlasbeyCollege of Medical and Dental Sciences University of Birmingham Birmingham UK.ORCID https://orcid.org/0000-0001-7688-5018
D MortonCollege of Medical and Dental Sciences University of Birmingham Birmingham UK.
N SmartExeter Surgical Health Services Research Unit Royal Devon and Exeter Hospital Exeter UK.
T PinkneyCollege of Medical and Dental Sciences University of Birmingham Birmingham UK.
A BhanguCollege of Medical and Dental Sciences University of Birmingham Birmingham UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAchieving stable closure of complex or contaminated abdominal wall incisions remains challenging. This study aimed to characterize the stage of innovation for biological mesh devices used during complex abdominal wall reconstruction and to evaluate the quality of current evidence.

methodsA systematic review was performed of published and ongoing studies between January 2000 and September 2017. Eligible studies were those where a biological mesh was used to support fascial closure, either prophylactically after midline laparotomy, or for reinforcement after repair of incisional hernia with midline incision. The primary outcome measure was the IDEAL framework stage of innovation. The key secondary outcome measure was the GRADE criteria for study quality.

resultsThirty-five studies including 2681 patients were included. Four studies considered mesh prophylaxis, 23 considered hernia repair, and eight reported on both. There was one published randomized trial (IDEAL stage 3), none of which was of high quality; the others were non-randomized studies (IDEAL stage 2a). A detailed description of surgical technique was provided in most studies (27 of 35); however, no study reported outcomes according to the European Hernia Society consensus statement and only two described quality control of surgical technique during the study. From 21 ongoing randomized trials and observational studies, 11 considered repair of incisional hernia and 10 considered prophylaxis (seven in elective settings).

conclusionThe evidence base for biological mesh is limited, and better reporting and quality control of surgical techniques are needed. Although results of ongoing trials over the next decade will improve the evidence base, further study is required in the emergency and contaminated settings.

Identifiers

PMID30511038
PMCPMC6254002

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.