ArticleData in brief2018
Data in support of toxicity studies of structurally modified plant virus to safety assessment.
Article in Data in brief, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Review
- Structurally Modified Plant Viruses and Bacteriophages with Helical Structure. Properties and Applications.Biochemistry. Biokhimiia · 2022Review
- Designing StablePharmaceutics · 2022Article
- Vaccine Candidate Against COVID-19 Based on Structurally Modified Plant Virus as an Adjuvant.Frontiers in microbiology · 2022Article
- Plant Viruses: New Opportunities under the Pandemic.Herald of the Russian Academy of Sciences · 2022Article
- New formulation of a recombinant anthrax vaccine stabilised with structurally modified plant viruses.Frontiers in microbiology · 2022Article
- Two approaches for the stabilization ofHuman vaccines & immunotherapeutics · 2021Article
- Thermal remodelling of Alternanthera mosaic virus virions and virus-like particles into protein spherical particles.PloS one · 2021Article
- Plant virus particles with various shapes as potential adjuvants.Scientific reports · 2020Article
- Various Adjuvants Effect on Immunogenicity of Puumala Virus Vaccine.Frontiers in cellular and infection microbiology · 2020Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This data article is related to the research article entitled "Assessment of structurally modified plant virus as a novel adjuvant in toxicity studies" (Nikitin et al., 2018), devoted to the safety study of structurally modified plant virus - spherical particles (SPs). SPs are generated by thermally denatured tobacco mosaic virus (TMV) coat protein and act as effective adjuvant for development of new vaccine candidates. This article reports the additional results on the toxicity studies of TMV SPs. The weight coefficients of laboratory animals internal organs complements the data of the subchronic toxicity studies. Also plaque-forming cell assay, delayed-type hypersensitivity test and peritoneal macrophage assay as a part of immunotoxicity studies of TMV SPs are presented.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.