Evidence map›Paper›PMID 30510971›Full record

ArticleAmerican journal of clinical and experimental urology2018

Voided volumes predict degree of partial bladder outlet obstruction in a murine model.

Nicholas M Tassone, Belinda Li, Megan Y Devine, Paulette M Hausner, Mehul S Patel, Andrew D Gould, Kirsten S Kochan, Robert W Dettman, Edward M Gong

Open access · greenAbstract read
In one paragraph

Article in American journal of clinical and experimental urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Nicholas M TassoneDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Belinda LiDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Megan Y DevineDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Paulette M HausnerDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Mehul S PatelDepartment of Urology, Feinberg School of Medicine, Northwestern University 303 E. Chicago Ave., 16-703, Chicago, IL 60611, USA.
Andrew D GouldDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Kirsten S KochanDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Robert W DettmanDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Edward M GongDepartment of Pediatric Urology, Ann & Robert H. Lurie Children's Hospital of Chicago 225 E. Chicago Ave., Chicago, IL 60611, USA.
Lurie Children's Hospital · USNorthwestern University · USDePaul University · USLoyola University Chicago · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The partial bladder outlet obstruction animal model (pBOO) is commonly used as a model for obstructive uropathy. Unfortunately, pBOO demonstrates variable degrees of obstruction requiring bladder weight (BW) or urodynamic studies to determine true obstruction. Our objective is to identify extent of obstruction by correlating early post-operative Void Stains on Paper (VSOP) assays with ultimate BW in mice. pBOO was performed on 32 mice 1- and 4-week VSOPs were quantified for mean voided volume (mVV). At 4 weeks, bladders were harvested and weighed. Correlation was evaluated through bivariate kernel density estimation and a Pearson correlation coefficient (SAS). Single variable histogram of the data established groups based on BWs and mVV. mVV's and bladder weights within group pairings were averaged and plotted to render a non-linear regression model. A significant correlation was found between 1-week mVVs and 4-week BWs upon bivariate analysis with a correlation coefficient of -0.758 (

Indexed as

Bladderbladder obstructionobstructive uropathypartial bladder outlet obstructionposterior urethral valvessurgical and invasive medical proceduresVSOP

Identifiers

PMID30510971
PMCPMC6261872
OpenAlexW2973691390

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.