Evidence map›Paper›PMID 30510942›Full record

ArticleWorld journal of clinical cases2018

Epstein-Barr virus-associated hemophagocytic syndrome in a patient with ulcerative colitis during treatment with azathioprine: A case report and review of literature.

Kazuya Miyaguchi, Minoru Yamaoka, Yoshikazu Tsuzuki, Keigo Ashitani, Hideki Ohgo, Yoshitaka Miyagawa, Keisuke Ishizawa, Hidekazu Kayano, Hidetomo Nakamoto, Hiroyuki Imaeda

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in World journal of clinical cases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 45% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Kazuya MiyaguchiDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Minoru YamaokaDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Yoshikazu TsuzukiDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Keigo AshitaniDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Hideki OhgoDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Yoshitaka MiyagawaDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Keisuke IshizawaDepartment of Pathology, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Hidekazu KayanoDepartment of Pathology, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Hidetomo NakamotoDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Hiroyuki ImaedaDepartment of General Internal Medicine, Saitama Medical University, Iruma-gun 350-0495, Saitama, Japan.
Creative Research Enterprises (United States) · USSaitama Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 19-year-old female was diagnosed with ulcerative colitis when she presented with persistent melena, and has been treated with 5-aminosalicylic acid for 4 years, with additional azathioprine for 2 years at our hospital. The patient experienced high-grade fevers, chills, and cough five d prior to presenting to the outpatient unit. At first, the patient was suspected to have developed neutropenic fever; however, she was diagnosed with Epstein-Barr virus-associated hemophagocytic syndrome (EB-VAHS) upon fulfilling the diagnostic criteria after bone marrow aspiration. When patients with inflammatory bowel disease treated with immunomodulators, such as thiopurine preparations, develop fever, EB-VAHS should be considered in the differential diagnosis.

Indexed as

AzathioprineCase reportInflammatory bowel diseaseUlcerative colitisVirus-associated hemophagocytic syndrome

Identifiers

PMID30510942
PMCPMC6264987
OpenAlexW2901501148

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.