Evidence map›Paper›PMID 30510935›Full record

ArticleFrontiers in veterinary science2018

Endochin-Like Quinolones Exhibit Promising Efficacy Against

Nicoleta Anghel, Vreni Balmer, Joachim Müller, Pablo Winzer, Adriana Aguado-Martinez, Mona Roozbehani, Sovitj Pou, Aaron Nilsen, Michael Riscoe, J Stone Doggett and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.8field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Microorganisms · 2026
    Review
  2. Transient Adaptation ofInternational journal of molecular sciences · 2024
    Article
  3. Synthesis of Deuterated Endochin-Like Quinolones.Journal of labelled compounds & radiopharmaceuticals · 2024
    Article
  4. Article
  5. Structure-activity relationships ofExpert opinion on drug discovery · 2022
    Article
  6. Dual inhibition of theFrontiers in veterinary science · 2022
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Activities of Endochin-Like Quinolones AgainstFrontiers in veterinary science · 2020
    Article
  14. Expert opinion on therapeutic targets
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 3 countries.

Nicoleta AnghelVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Vreni BalmerVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Joachim MüllerVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Pablo WinzerVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Adriana Aguado-MartinezVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
Mona RoozbehaniDepartment of Parasitology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Sovitj PouVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Aaron NilsenVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Michael RiscoeVA Portland Health Care System Research and Development Service, Portland, OR, United States.
J Stone DoggettVA Portland Health Care System Research and Development Service, Portland, OR, United States.
Andrew HemphillVetsuisse Faculty, Institute of Parasitology, University of Bern, Bern, Switzerland.
University of Bern · CHVA Portland Health Care System · USIran University of Medical Sciences · IR

Funding

Optimizing ELQs for Treatment and Prevention of MalariaR01AI100569 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI Michael Kevin RISCOE · 2014 to 2026
$8.0M
Development of the potent anti-malarial and anti-Toxoplasma drug, ELQ-316IK2BX002440 · VA · PORTLAND VA MEDICAL CENTER · PI DOGGETT, JOSEPH STONE · 2014 to 2018
–
BLRD VA IK2 BX002440NIAID NIH HHS R01 AI100569
6 · The paper itself

Abstract

We report on the efficacy of selected endochin-like quinolones (ELQs) against

Indexed as

cytochromebelectron microscopyendochin-like quinolonesmitochondrionmouse modelNeosporaToxoplasmavertical transmission

Identifiers

PMID30510935
PMCPMC6252379
OpenAlexW2901093943

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.