Evidence map›Paper›PMID 30510917›Full record

ArticleFrontiers in cellular and infection microbiology2018

Phenotypic and Functional Profiles of Antigen-Specific CD4

Adriana Egui, Darién Ledesma, Elena Pérez-Antón, Andrés Montoya, Inmaculada Gómez, Sara María Robledo, Juan José Infante, Ivan Darío Vélez, Manuel C López, M Carmen Thomas

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 37 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Upregulation of CD244 promotes CD8Parasites & vectors · 2024
    Article
  5. The Role of Senescent CD8Pathogens (Basel, Switzerland) · 2024
    Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Increased amphiregulin expression by CD4Clinical & translational immunology · 2022
    Article
  16. Review
  17. Viruses · 2021
    Article
  18. Article
  19. Revival of Leishmanization and Leishmanin.Frontiers in cellular and infection microbiology · 2021
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Adriana EguiMolecular Biology Department, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas, Granada, Spain.
Darién LedesmaMolecular Biology Department, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas, Granada, Spain.
Elena Pérez-AntónMolecular Biology Department, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas, Granada, Spain.
Andrés MontoyaPrograma de Estudio y Control de Enfermedades Tropicales, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Inmaculada GómezMolecular Biology Department, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas, Granada, Spain.
Sara María RobledoPrograma de Estudio y Control de Enfermedades Tropicales, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Juan José InfanteBionaturis Group, Bioorganic Research and Services, S.A., Jerez de la Frontera, Spain.
Ivan Darío VélezPrograma de Estudio y Control de Enfermedades Tropicales, Facultad de Medicina, Universidad de Antioquia, Medellín, Colombia.
Manuel C LópezMolecular Biology Department, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas, Granada, Spain.
M Carmen ThomasMolecular Biology Department, Instituto de Parasitología y Biomedicina "López Neyra", Consejo Superior de Investigaciones Científicas, Granada, Spain.
Instituto de Parasitología y Biomedicina "López - Neyra" · ESUniversidad de Antioquia · COConsejo Superior de Investigaciones Científicas · ESHospital Jerez Puerta del Sur · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The host immunological response is a key factor determining the pathogenesis of cutaneous leishmaniasis. It is known that a Th1 cellular response is associated with infection control and that antigen-specific memory T cells are necessary for the development of a rapid and strong protective cellular response. The present manuscript reports the analysis of the functional and phenotypic profiles of antigen-specific CD4

Indexed as

Infection ControlAntigens, CDAntigens, ProtozoanCD4 AntigensCD4-Positive T-LymphocytesCD57 AntigensCD8-Positive T-LymphocytesCell ProliferationCytokinesGPI-Linked ProteinsGranzymesHumansInterferon-gammaLeishmaniaLeishmania infantumLeishmaniasis, CutaneousAntigens, CDAntigens, ProtozoanCD160 protein, humanCD4 AntigensCD57 AntigensCytokinesGPI-Linked ProteinsGranzymesInterferon-gammaPerforinProtozoan ProteinsReceptors, ImmunologicRecombinant ProteinsbiomarkersCD8+ and CD4+ T-cellsinhibitory receptorsLeishmanialeishmaniasisparaflagellar rod protein-1phenotypeTh1-cytokines

Identifiers

PMID30510917
PMCPMC6252334
OpenAlexW2900681937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.