Evidence map›Paper›PMID 30510674›Full record

ArticleChemical science2018

Multi-omics and temporal dynamics profiling reveal disruption of central metabolism in

Bingjie Han, Zhen Zhang, Yanxuan Xie, Xuqiao Hu, Haibo Wang, Wei Xia, Yulan Wang, Hongyan Li, Yuchuan Wang, Hongzhe Sun

Open access · diamondAbstract read
In one paragraph

Article in Chemical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Modulating the microbiome as an approach to anticancer drug development.Proceedings of the National Academy of Sciences of the United States of America · 2025
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  8. Article
  9. Article
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  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Insulin-Mimic Components inPharmaceuticals (Basel, Switzerland) · 2021
    Article
  18. Article
  19. Review of current diagnostic methods and advances inWorld journal of gastroenterology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Bingjie HanSchool of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: wangych55@mail.sysu.edu.cn.
Zhen ZhangSchool of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: wangych55@mail.sysu.edu.cn.
Yanxuan XieSchool of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: wangych55@mail.sysu.edu.cn.
Xuqiao HuDepartment of Chemistry , The University of Hong Kong , Hong Kong , P. R. China . Email: hsun@hku.hk.
Haibo WangDepartment of Chemistry , The University of Hong Kong , Hong Kong , P. R. China . Email: hsun@hku.hk.
Wei XiaSchool of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: wangych55@mail.sysu.edu.cn.ORCID 0000-0001-6480-3265
Yulan WangCAS Key Laboratory of Magnetic Resonance in Biological Systems , State Key Laboratory of Magnetic Resonance and Atomic and Molecular Physics , Wuhan Institute of Physics and Mathematics , Chinese Academy of Sciences , Wuhan , 430071 , P. R. China.
Hongyan LiDepartment of Chemistry , The University of Hong Kong , Hong Kong , P. R. China . Email: hsun@hku.hk.ORCID 0000-0002-1158-5871
Yuchuan WangSchool of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: wangych55@mail.sysu.edu.cn.ORCID 0000-0002-1137-9744
Hongzhe SunSchool of Chemistry , Sun Yat-sen University , Guangzhou , 510275 , P. R. China . Email: wangych55@mail.sysu.edu.cn.ORCID 0000-0001-6697-6899
Sun Yat-sen University · CNUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Integration of multi-omics enables uncovering cellular responses to stimuli or the mechanism of action of a drug at a system level. Bismuth drugs have long been used for the treatment of

Identifiers

PMID30510674
PMCPMC6223348
OpenAlexW2884186750

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.