Evidence map›Paper›PMID 30510570›Full record

ArticleGastroenterology research and practice2018

Antichronic Gastric Ulcer Effect of Zinc-Baicalin Complex on the Acetic Acid-Induced Chronic Gastric Ulcer Rat Model.

Hui Yang, Yi Lu, Xiao-Feng Zeng, Ling Li, Rong-Ping Zhang, Zhong-Kun Ren, Xu Liu

Open access · goldAbstract read
In one paragraph

Article in Gastroenterology research and practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
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  7. Gastro-Protective and Anti-Oxidant Potential ofAntioxidants (Basel, Switzerland) · 2019
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hui YangBiomedical Engineering Center, Kunming Medical University, Kunming 650500, China.ORCID 0000-0001-5011-7838
Yi LuNeurosurgery, The 1st Affiliated Hospital of Kunming Medical University, Kunming 650032, China.
Xiao-Feng ZengSchool of Forensic Medicine, Kunming Medical University, Kunming 650500, China.
Ling LiBiomedical Engineering Center, Kunming Medical University, Kunming 650500, China.
Rong-Ping ZhangBiomedical Engineering Center, Kunming Medical University, Kunming 650500, China.
Zhong-Kun RenNeurosurgery, The 1st Affiliated Hospital of Kunming Medical University, Kunming 650032, China.ORCID 0000-0001-8284-874X
Xu LiuBiomedical Engineering Center, Kunming Medical University, Kunming 650500, China.ORCID 0000-0001-6097-5553
Kunming Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBaicalin (BA) has been shown to have anti-inflammatory and antioxidant activity. Zinc is a nutrient element.

objectiveThis study is aimed at investigating the antichronic gastric ulcer activity of Zn-Baicalin complex (BA-Zn) and its related mechanisms in an acetic acid-induced gastric ulcer rat model.

resultsThe severely ulcerated gastric mucosa of model rats had lower GSH-Px (52.21 ± 7.13) and SOD (7.03 ± 0.10) activity, and higher MDA (2.39 ± 0.03) content compared to sham rats. BA-Zn reduced the gastric ulcer index in a dose-dependent manner, significantly increased SOD activity and GSH-Px level, and reduced the MDA content and IL-8 and TNF-

conclusionThe BA-Zn complex possesses greater antichronic gastric ulcer properties compared to BA and zinc-gluconate due to its ability of oxidation resistance and anti-inflammatory effects.

Identifiers

PMID30510570
PMCPMC6230421
OpenAlexW2898574663

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.