ArticleFrontiers in physiology2018
High-Intensity Exercise Mitigates Cardiovascular Deconditioning During Long-Duration Bed Rest.
Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed, 30 citations in OpenAlex.
- Time-series analysis of heart rate and blood pressure in response to changes in work rate before and after 60 days of 6° head down tilt bed rest.European journal of applied physiology · 2021Trial
- The impact of 14-day head-down bed rest with or without an exercise countermeasure on standing balance control: a randomized controlled trial.NPJ microgravity · 2026Article
- Effects of jump training on power, strength, balance and aerobic performance in non-exercising young adults.Frontiers in sports and active living · 2026Article
- Evidence of effective cardiovascular countermeasures during spaceflights: insights from wearable monitoring.NPJ microgravity · 2025Article
- Heart rate variability adaptation due to head-down tilt bed rest: insights from pooled data of six campaigns.NPJ microgravity · 2025Article
- Cardiac vagal modulation predicts decision-making in sacrificial and everyday moral dilemmas.Scientific reports · 2025Article
- Cardiomyocyte external mechanical unloading activates modifications of α-actinin differently from sarcomere-originated unloading.The FEBS journal · 2023Article
- Gravitational effects on carotid and jugular characteristics in graded head-up and head-down tilt.Journal of applied physiology (Bethesda, Md. : 1985) · 2023Article
- Article
- Implementation of exercise countermeasures during spaceflight and microgravity analogue studies: Developing countermeasure protocols for bedrest in older adults (BROA).Frontiers in physiology · 2022Review
- Cardiovascular deconditioning and impact of artificial gravity during 60-day head-down bed rest-Insights from 4D flow cardiac MRI.Frontiers in physiology · 2022Article
- Modeling individual differences in cardiovascular response to gravitational stress using a sensitivity analysis.Journal of applied physiology (Bethesda, Md. : 1985) · 2021Article
- Gravitational Influence on Human Living Systems and the Evolution of Species on Earth.Molecules (Basel, Switzerland) · 2021Review
- Cardiovascular adaptation to simulated microgravity and countermeasure efficacy assessed by ballistocardiography and seismocardiography.Scientific reports · 2020Article
- Vascular and Microvascular Dysfunction Induced by Microgravity and Its Analogs in Humans: Mechanisms and Countermeasures.Frontiers in physiology · 2020Review
- Adaptability of a jump movement pattern to a non-constant force field elicited via centrifugation.PloS one · 2020Article
- The Importance of Impact Loading and the Stretch Shortening Cycle for Spaceflight Countermeasures.Frontiers in physiology · 2019Review
- Reactive Jumps Preserve Skeletal Muscle Structure, Phenotype, and Myofiber Oxidative Capacity in Bed Rest.Frontiers in physiology · 2019Article
- Long-Term Microgravity Exposure Increases ECG Repolarization Instability Manifested by Low-Frequency Oscillations of T-Wave Vector.Frontiers in physiology · 2019Article
Corrections and comments
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Authors and funding
11 authors at 4 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Head-down-tilt bed rest (HDT) mimics the changes in hemodynamics and autonomic cardiovascular control induced by weightlessness. However, the time course and reciprocal interplay of these adaptations, and the effective exercise protocol as a countermeasure need further clarification. The overarching aim of this work (as part of a European Space Agency sponsored long-term bed rest study) was therefore to evaluate the time course of cardiovascular hemodynamics and autonomic control during prolonged HDT and to assess whether high-intensity, short-duration exercise could mitigate these effects. A total of
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.