ArticleNature microbiology2019
Viruses control dominant bacteria colonizing the terrestrial deep biosphere after hydraulic fracturing.
Article in Nature microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 63 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
63 citing papers in PubMed.
- Ecological plasticity ofMicrobiology spectrum · 2026Article
- Cross-family and phage-specific gene requirements for Klebsiella infection revealed by scalable RB-TnSeq genetic screens.PLoS genetics · 2026Article
- Bacteriophages in the Rhizosphere: Roles in Nutrient Cycling, Bacterial Community Structure, and Animal-Mediated Dispersal.MicrobiologyOpen · 2026Review
- Viromics approaches for the study of viral diversity and ecology in microbiomes.Nature reviews. Genetics · 2026Review
- Subsurface microbiology and the pressing societal need to support future exploration.FEMS microbiology ecology · 2025Review
- Multi-domain temporal patterns reveal stable community membership but dynamic interactions in the coastal microbiome.Environmental microbiome · 2025Article
- DNA viral community enhances microbial carbon fixation capacity via auxiliary metabolic genes in contaminated soils.Nature communications · 2025Article
- Significant impact of bleaching treatment on phage-host interaction dynamics in a full-scale wastewater treatment plant.Scientific reports · 2025Article
- Anthropogenic impacts on the terrestrial subsurface biosphere.Nature reviews. Microbiology · 2025Review
- Ecological features of microbial community linked to stochastic and deterministic assembly processes in acid mine drainage.Applied and environmental microbiology · 2025Article
- Isolation and characterization of 24 phages infecting the plant growth-promoting rhizobacterium Klebsiella sp. M5al.PloS one · 2025Article
- Viral communities in a pH>10 serpentinite-like environment: insight into diversity and potential roles in modulating the microbiomes by bioactive vitamin BApplied and environmental microbiology · 2024Article
- Global diversity and ecological functions of viruses inhabiting oil reservoirs.Nature communications · 2024Article
- Unveiling the unknown viral world in groundwater.Nature communications · 2024Article
- Viruses contribute to microbial diversification in the rumen ecosystem and are associated with certain animal production traits.Microbiome · 2024Article
- Predictions of rhizosphere microbiome dynamics with a genome-informed and trait-based energy budget model.Nature microbiology · 2024Article
- Time-series metaproteogenomics of a high-COmicroLife · 2024Article
- Viral diversity and host associations in microbial electrolysis cells.ISME communications · 2024Article
- Mixed waste contamination selects for a mobile genetic element population enriched in multiple heavy metal resistance genes.ISME communications · 2024Article
- Geochemical constraints on bacteriophage infectivity in terrestrial environments.ISME communications · 2023Article
3 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The deep terrestrial biosphere harbours a substantial fraction of Earth's biomass and remains understudied compared with other ecosystems. Deep biosphere life primarily consists of bacteria and archaea, yet knowledge of their co-occurring viruses is poor. Here, we temporally catalogued viral diversity from five deep terrestrial subsurface locations (hydraulically fractured wells), examined virus-host interaction dynamics and experimentally assessed metabolites from cell lysis to better understand viral roles in this ecosystem. We uncovered high viral diversity, rivalling that of peatland soil ecosystems, despite low host diversity. Many viral operational taxonomic units were predicted to infect Halanaerobium, the dominant microorganism in these ecosystems. Examination of clustered regularly interspaced short palindromic repeats-CRISPR-associated proteins (CRISPR-Cas) spacers elucidated lineage-specific virus-host dynamics suggesting active in situ viral predation of Halanaerobium. These dynamics indicate repeated viral encounters and changing viral host range across temporally and geographically distinct shale formations. Laboratory experiments showed that prophage-induced Halanaerobium lysis releases intracellular metabolites that can sustain key fermentative metabolisms, supporting the persistence of microorganisms in this ecosystem. Together, these findings suggest that diverse and active viral populations play critical roles in driving strain-level microbial community development and resource turnover within this deep terrestrial subsurface ecosystem.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.