Evidence map›Paper›PMID 30510101›Full record

ArticleInfection and immunity2019

Downregulation of the Central Noradrenergic System by

Isra Alsaady, Ellen Tedford, Mohammad Alsaad, Greg Bristow, Shivali Kohli, Matthew Murray, Matthew Reeves, M S Vijayabaskar, Steven J Clapcote, Jonathan Wastling and 1 more

Open access · bronzeAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
2.5field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 37 citations in OpenAlex.

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  7. Effects of diet and ovariectomy onBrain communications · 2025
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  10. BMJ open · 2024
    Observational
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  13. Toxoplasma-induced behavior changes - is microbial dysbiosis the missing link?Frontiers in cellular and infection microbiology · 2024
    Review
  14. Editorial: Rising stars in parasite and host: 2023.Frontiers in cellular and infection microbiology · 2024
    Article
  15. Article
  16. Review
  17. Epigenetic Manipulation of Psychiatric Behavioral Disorders Induced byFrontiers in cellular and infection microbiology · 2022
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Isra Alsaady *School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Ellen Tedford *School of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Mohammad AlsaadSchool of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Greg BristowSchool of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Shivali KohliSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Matthew MurrayInstitute of Immunity & Transplantation, UCL Department of Virology, Division of Infection & Immunity, Royal Free Hospital, London, United Kingdom.
Matthew ReevesInstitute of Immunity & Transplantation, UCL Department of Virology, Division of Infection & Immunity, Royal Free Hospital, London, United Kingdom.
M S VijayabaskarSchool of Molecular and Cellular Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Steven J ClapcoteSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Jonathan WastlingFaculty of Natural Sciences, University of Keele, Newcastle-under-Lyme, United Kingdom.
Glenn A McConkeySchool of Biology, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom G.A.McConkey@Leeds.ac.uk.ORCID 0000-0001-6529-794X
University of Leeds · GBThe Royal Free Hospital · GBKeele University · GB

Funding

Medical Research Council G0900466Medical Research Council G0900625
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsBrainCatecholaminesCentral Nervous System DiseasesDopamineDopamine beta-HydroxylaseDown-RegulationGene Expression RegulationMiceNeuronsNorepinephrineRatsRNA, MessengerToxoplasmosisCatecholaminesDopamineDopamine beta-HydroxylaseNorepinephrineRNA, Messengerapicomplexan parasitesbehaviorbradyzoitehost-pathogen interactionsintracellular parasitesnorepinephrineprotozoa

Identifiers

PMID30510101
PMCPMC6346129
OpenAlexW2808614643

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.