Evidence map›Paper›PMID 30509983›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2018

Mycoplasma promotes malignant transformation in vivo, and its DnaK, a bacterial chaperone protein, has broad oncogenic properties.

Davide Zella, Sabrina Curreli, Francesca Benedetti, Selvi Krishnan, Fiorenza Cocchi, Olga S Latinovic, Frank Denaro, Fabio Romerio, Muhammad Djavani, Man E Charurat and 3 more

Erratum issuedOpen access · bronzeAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 44 papers.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed
4.6field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Review
  3. Genomic Characterization of aVeterinary sciences · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Mycoplasma DnaK expression increases cancer development in vivo upon DNA damage.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
  10. Identification of potential nucleomodulins ofFrontiers in microbiology · 2024
    Article
  11. Heliyon · 2023
    Article
  12. Mycoplasma DnaK increases DNA copy number variants in vivo.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  13. Review
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Characterization of the interactome profiling ofFrontiers in microbiology · 2022
    Article
  20. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Davide ZellaInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201; dzella@ihv.umaryland.edu rgallo@ihv.umaryland.edu.
Sabrina CurreliInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Francesca BenedettiInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Selvi KrishnanInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Fiorenza CocchiInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Olga S LatinovicInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Frank DenaroDepartment of Biology, Morgan State University, Baltimore, MD 21251.
Fabio RomerioInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Muhammad DjavaniInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Man E CharuratInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Joseph L BryantInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Hervé TettelinDepartment of Microbiology and Immunology, School of Medicine, University of Maryland, Baltimore, MD 21201.
Robert C GalloInstitute of Human Virology, School of Medicine, University of Maryland, Baltimore, MD 21201; dzella@ihv.umaryland.edu rgallo@ihv.umaryland.edu.
University of Maryland, Baltimore · USMorgan State University · US

Funding

Project-002UL1GM118973 · NIGMS · MORGAN STATE UNIVERSITY · PI KAMANGAR, FARIN · 2015 to 2023
$18.8M
NIGMS NIH HHS UL1 GM118973
6 · The paper itself

Abstract

We isolated a strain of human mycoplasma that promotes lymphomagenesis in SCID mice, pointing to a p53-dependent mechanism similar to lymphomagenesis in uninfected p53

Indexed as

Adenosine TriphosphatasesAnimalsAntineoplastic AgentsBacterial ProteinsCarcinogenesisCell Transformation, NeoplasticDisease Models, AnimalDNA-Activated Protein KinaseDNA, BacterialDNA RepairGenes, BacterialHCT116 CellsHSP70 Heat-Shock ProteinsHumansLymphomaMiceAdenosine TriphosphatasesAntineoplastic AgentsBacterial ProteinsDNA-Activated Protein KinaseDNA, BacterialDnaK protein, Brevibacillus choshinensisHSP70 Heat-Shock ProteinsMolecular ChaperonesPARP1 protein, humanParp1 protein, mousePoly (ADP-Ribose) Polymerase-1Tumor Suppressor Protein p53Ubiquitin ThiolesteraseUSP10 protein, mousecancerDnaKDNA repairmycoplasmap53

Identifiers

PMID30509983
PMCPMC6304983
OpenAlexW2903263256

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.