Evidence map›Paper›PMID 30509964›Full record

SynthesisBioscience reports2019

A trial sequential meta-analysis of

Raju K Mandal, Munawwar Ali Khan, Arif Hussain, Naseem Akhter, Arshad Jawed, Sajad A Dar, Mohd Wahid, Aditya K Panda, Mohtashim Lohani, Bhartendu N Mishra and 1 more

Open access · goldAbstract readMeta-Analysis
In one paragraph

Synthesis in Bioscience reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Raju K MandalResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan-45142, Saudi Arabia.
Munawwar Ali KhanDepartment of Life and Environmental Sciences, College of Natural and Health Sciences, Zayed University, P.O. Box 19282, Dubai, United Arab Emirates.
Arif HussainSchool of Life Sciences, Manipal Academy of Higher Education, P.O. Box 345050, Dubai, United Arab Emirates.
Naseem AkhterDepartment of Laboratory Medicine, Faculty of Applied Medical Sciences, Albaha University, Albaha 65431, Saudi Arabia.
Arshad JawedResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan-45142, Saudi Arabia.
Sajad A DarResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan-45142, Saudi Arabia.
Mohd WahidResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan-45142, Saudi Arabia.
Aditya K PandaCentre for Life Sciences, Central University of Jharkhand, Ranchi 835205, Jharkhand, India.
Mohtashim LohaniDepartment of Emergency Medical Services, College of Applied Medical Sciences, Jazan University, Jazan 45142, Saudi Arabia.
Bhartendu N MishraDepartment of Biotechnology, Institute of Engineering and Technology, Lucknow 226021, Uttar Pradesh, India.
Shafiul HaqueResearch and Scientific Studies Unit, College of Nursing and Allied Health Sciences, Jazan University, Jazan-45142, Saudi Arabia shafiul.haque@hotmail.com.ORCID 0000-0002-2989-121X
Jazan University · SAAl Baha University · SACentral University of Jharkhand · INZayed University · AE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTumor necrosis factor-α (TNF-α), secreted by the activated macrophages, may participate in the onset and progression of colorectal cancer (CRC). The association of

methodsMedline (PubMed), EMBASE (Excerpta-Medica) and Google Scholar were mined for relevant articles. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to estimate the significance of association.

resultsThe pooled analysis indicated no risk associated with

conclusionsNo association of

Indexed as

Polymorphism, Single NucleotidePromoter Regions, GeneticAsian PeopleClinical Trials as TopicColorectal NeoplasmsGene ExpressionGenotypeHeterozygoteHomozygoteHumansModels, GeneticOdds RatioTumor Necrosis Factor-alphaWhite PeopleTumor Necrosis Factor-alphaColorectal cancerMeta-analysispolymorphismsusceptibilityTumor Necrosis Factor-α

Identifiers

PMID30509964
PMCPMC6331670
OpenAlexW2902409708

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.