ArticleGenes & development2018
Evolution of aneuploidy: overcoming the original CIN.
Article in Genes & development, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- Aneuploidy Is Associated with Azole Resistance in Aspergillus fumigatus.Antimicrobial agents and chemotherapy · 2023Article
- A quantitative and semiautomated method for determining misaligned and lagging chromosomes during mitosis.Molecular biology of the cell · 2021Article
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1 author.
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No grant is acknowledged in the PubMed record.
Abstract
Chromosomal instability (CIN) generates continuously novel aneuploid genomes-unbalanced chromosome combinations that differ from the haploid chromosome set and its multiples. On one hand, this causes problems for cells, as high CIN and aneuploidy impair cellular proliferation by inducing multiple cellular stresses. At the same time, some genomes might provide an advantage under suboptimal conditions. However, what happens to cells that carry a mutation generating extremely high CIN? Are they sentenced to death, or can their instability help them to avert that fate? The elegant work from Ravichandran and colleagues (pp. 1485-1498) in this issue of
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