Evidence map›Paper›PMID 30509945›Full record

ArticleAntimicrobial agents and chemotherapy2019

Mutations in

Truc T Tran, Nagendra N Mishra, Ravin Seepersaud, Lorena Diaz, Rafael Rios, An Q Dinh, Cristina Garcia-de-la-Maria, Michael J Rybak, Jose M Miro, Samuel A Shelburne and 3 more

Open access · bronzeAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
3.0field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 27 citations in OpenAlex.

  1. Article
  2. Pan-genome analysis ofFrontiers in microbiology · 2024
    Article
  3. Membrane Phenotypic, Metabolic and Genotypic Adaptations ofAntibiotics (Basel, Switzerland) · 2023
    Article
  4. Comparison of Phenotype and Genotype Virulence and Antimicrobial Factors ofInternational journal of molecular sciences · 2023
    Article
  5. Review
  6. Article
  7. Article
  8. Development of High-Level Daptomycin Resistance inAntimicrobial agents and chemotherapy · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Strain-Specific Adaptations ofAntibiotics (Basel, Switzerland) · 2020
    Article
  13. Article
  14. Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 4 countries.

Truc T TranCenter for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA.
Nagendra N MishraLA Biomedical Research Institute, Torrance, California, USA.
Ravin SeepersaudUniversity of California, San Francisco, California, USA.
Lorena DiazCenter for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA.
Rafael RiosCenter for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA.
An Q DinhCenter for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA.
Cristina Garcia-de-la-MariaHospital Clinic, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Michael J RybakAnti-Infective Research Laboratory, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
Jose M MiroHospital Clinic, Institut d'Investigacions Biomèdiques August Pi I Sunyer (IDIBAPS), University of Barcelona, Barcelona, Spain.
Samuel A ShelburneDepartment of Infectious Diseases and Infection Control, University of Texas MD Anderson Cancer Center, Houston, Texas, USA.
Paul M SullamUniversity of California, San Francisco, California, USA.
Arnold S BayerLA Biomedical Research Institute, Torrance, California, USA.
Cesar A AriasCenter for Antimicrobial Resistance and Microbial Genomics and Division of Infectious Diseases, UTHealth McGovern Medical School, Houston, Texas, USA cesar.arias@uth.tmc.edu.
The University of Texas Health Science Center at Houston · USConsorci Institut D'Investigacions Biomediques August Pi I Sunyer · ESUniversidad El Bosque · COUniversity of California, Los Angeles · USSan Francisco VA Medical Center · USThe University of Texas MD Anderson Cancer Center · USUniversity of California, San Francisco · USWayne State University · US

Funding

STREPTOCOCCAL PLATELET BINDING AND ENDOCARDITISR01AI041513 · NIAID · NORTHERN CALIFORNIA INSTITUTE RES &EDUC · PI SULLAM, PAUL M. · 1997 to 2019
$5.6M
The LiaFSR system and antimicrobial peptide resistance in enterococciR01AI134637 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI Cesar Augusto Arias · 2018 to 2026
$3.7M
Mechanisms and Circumvention of Daptomycin Resistance in Streptococcus mitisR01AI130056 · NIAID · LUNDQUIST INSTITUTE FOR BIOMEDICAL INNOVATION AT HARBOR-UCLA MEDICAL CENTER · PI BAYER, ARNOLD S · 2018 to 2022
$2.4M
A Pharmacologic Approach to Prevent Daptomycin Resistance in VRER01AI121400 · NIAID · WAYNE STATE UNIVERSITY · PI RYBAK, MICHAEL JOSEPH · 2016 to 2020
$1.9M
POR Program on Genomic Prediction of Antimicrobial Resistance in VREK24AI121296 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ARIAS, CESAR AUGUSTO · 2016 to 2025
$1.5M
Daptomycin Resistance in Enterococcus faeciumK08AI113317 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI TRAN, TRUC THANH · 2014 to 2018
$792k
Molecular basis of the cefazolin inoculum effectR21AI143229 · NIAID · UNIVERSITY OF TEXAS HLTH SCI CTR HOUSTON · PI ARIAS, CESAR AUGUSTO · 2019 to 2020
$442k
Impact of daptomycin dose exposure on biofilm embedded Enterococci resistanceR21AI109266 · NIAID · WAYNE STATE UNIVERSITY · PI RYBAK, MICHAEL JOSEPH · 2014 to 2015
$380k
NIAID NIH HHS K08 AI113317NIAID NIH HHS K24 AI121296NIAID NIH HHS R01 AI041513NIAID NIH HHS R01 AI121400NIAID NIH HHS R01 AI130056NIAID NIH HHS R01 AI134637NIAID NIH HHS R21 AI109266NIAID NIH HHS R21 AI143229
6 · The paper itself

Abstract

We investigated the ability of several recent clinical viridans group streptococci (VGS) bloodstream isolates (

Indexed as

Anti-Bacterial AgentsCardiolipinsCell MembraneDaptomycinDrug Resistance, BacterialHumansMicrobial Sensitivity TestsNucleotidyltransferasesPhosphatidylglycerolsStreptococcus mitisStreptococcus oralisTransferases (Other Substituted Phosphate Groups)Anti-Bacterial AgentsCardiolipinsCDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferaseDaptomycinNucleotidyltransferasesphosphatidate cytidylyltransferasePhosphatidylglycerolsTransferases (Other Substituted Phosphate Groups)CdsAdaptomycin resistancePgsAStreptococcus mitis

Identifiers

PMID30509945
PMCPMC6355606
OpenAlexW2902211914

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.