Evidence map›Paper›PMID 30509349›Full record

ArticleeLife2018

Membrane fluidity is regulated by the

Mario Ruiz, Rakesh Bodhicharla, Emma Svensk, Ranjan Devkota, Kiran Busayavalasa, Henrik Palmgren, Marcus Ståhlman, Jan Boren, Marc Pilon

Open access · goldAbstract read
In one paragraph

Article in eLife, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 63 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Forward genetics ineLife · 2025
    Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Beyond Fluidity: The Role of Lipid Unsaturation in Membrane Function.Cold Spring Harbor perspectives in biology · 2023
    Review
  18. Article
  19. Review
  20. Multi-omics analysis of TLCD1 as a promising biomarker in pan-cancer.Frontiers in cell and developmental biology · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Mario Ruiz *Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Rakesh Bodhicharla *Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Emma Svensk *Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Ranjan DevkotaDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Kiran BusayavalasaDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Henrik PalmgrenDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.
Marcus StåhlmanDepartment of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-4202-0339
Jan BorenDepartment of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, University of Gothenburg, Gothenburg, Sweden.
Marc PilonDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0003-3919-2882
University of Gothenburg · SEAstraZeneca (Sweden) · SE

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
NIH HHS P40 OD010440
6 · The paper itself

Abstract

Dietary fatty acids are the main building blocks for cell membranes in animals, and mechanisms must therefore exist that compensate for dietary variations. We isolated Editorial note: This article has been through an editorial process in which the authors decide how to respond to the issues raised during peer review. The Reviewing Editor's assessment is that all the issues have been addressed (see decision letter).

Indexed as

Membrane FluiditySequence Homology, Amino AcidAllelesAmino Acid SequenceAnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsCell MembraneEpistasis, GeneticGenes, SuppressorGreen Fluorescent ProteinsHumansMembrane ProteinsMiceMutationOrgan SpecificityCaenorhabditis elegans ProteinsFLD-1 protein, C elegansGreen Fluorescent ProteinsMembrane ProteinsPhospholipidsReceptors, AdiponectinTLCD1 protein, humanTLCD2 protein, humanC. eleganscell biologyfluorescence recovery after photobleachingforward geneticshumanlipotoxicitymembrane fluiditymembrane homeostasisphospholipid

Identifiers

PMID30509349
PMCPMC6279351
OpenAlexW2903300435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.