Evidence map›Paper›PMID 30509250›Full record

ReviewJournal of biomedical science2018

A new approach to study the sex differences in adipose tissue.

Sarah Jayne Fitzgerald, Amol Vijay Janorkar, Allison Barnes, Rodrigo Oscar Maranon

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of biomedical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

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  16. Effect of Supplementation with Hydroethanolic Extract ofMolecules (Basel, Switzerland) · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sarah Jayne FitzgeraldDepartment of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, Jackson, USA.
Amol Vijay JanorkarDepartment of Biomedical Materials Science, School of Dentistry, University of Mississippi Medical Center, Jackson, USA.
Allison BarnesDepartment of Cell and Molecular Biology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216, USA.
Rodrigo Oscar MaranonDepartment of Cell and Molecular Biology, University of Mississippi Medical Center, 2500 North State Street, Jackson, MS, 39216, USA. rmaranon@umc.edu.ORCID http://orcid.org/0000-0002-3743-7420
State Street (United States) · USUniversity of Mississippi Medical Center · US

Funding

Role of obesity in preeclamptic pregnancy.P20GM121334 · NIGMS · UNIVERSITY OF MISSISSIPPI MED CTR · PI Babbette LaMarca, Jane F Reckelhoff · 2017 to 2026
$26.4M
3D Spheroid Model of Adipose PathophysiologyR01EB020006 · NIBIB · UNIVERSITY OF MISSISSIPPI MED CTR · PI JANORKAR, AMOL VIJAY · 2016 to 2019
$1.4M
National Institute Of General Medical Sciences of the National Institutes of Health P20GM121334NIBIB NIH HHS R01 EB020006NIGMS NIH HHS P20 GM121334
6 · The paper itself

Abstract

Obesity is one of the most invaliding and preventable diseases in the United States. Growing evidence suggests that there are sex differences in obesity in human and experimental animals. However, the specific mechanisms of this disease are unknown. Consequently, there is any particular treatment according to the sex/gender at this time. During the last decade, we observe a rise in the study of adipocyte and the possible mechanisms involved in the different roles of the fat. Furthermore, the effect of sex steroids on the adipocyte is one of the fields that need elucidation. Supporting evidence suggests that sex steroids play an essential role not only in the fat distribution, but also, in its metabolism, proliferation, and function. Thus, using in vitro and in vivo studies will contribute to our fight against this critical health public problem encompassing both sexes. In the present review, we discuss some of the recent advances in the adipocytes and the effect of the sex steroids on the adipose tissue. Also, we propose a new alternative to study the role of sex steroids on adipocyte biology through human adipose-derived stem cells.

Indexed as

AdipocytesAnimalsFemaleGonadal Steroid HormonesHumansMaleMiceRatsSex FactorsGonadal Steroid HormonesAdipocytesObesitySex differencesStem cells

Identifiers

PMID30509250
PMCPMC6278144
OpenAlexW2903517072

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.