Evidence map›Paper›PMID 30509249›Full record

ArticleBMC palliative care2018

Quality of life in men with metastatic prostate cancer in their final years before death - a retrospective analysis of prospective data.

Maja Holm, Sandra Doveson, Olav Lindqvist, Agneta Wennman-Larsen, Per Fransson

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In one paragraph

Article in BMC palliative care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  20. Unmet supportive care needs in prostate cancer survivors with advanced disease: A mixed-methods exploration.Canadian oncology nursing journal = Revue canadienne de nursing oncologique · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Maja HolmDepartment of Nursing Sciences, Sophiahemmet University, Box 5606, 114 28, Stockholm, Sweden. maja.holm@shh.se.ORCID http://orcid.org/0000-0003-2074-5985
Sandra DovesonDepartment of Nursing Sciences, Sophiahemmet University, Box 5606, 114 28, Stockholm, Sweden.
Olav LindqvistDepartment of Learning, Informatics, Management & Ethics, Karolinska Institutet., 171 77, Stockholm, Sweden.
Agneta Wennman-LarsenDepartment of Nursing Sciences, Sophiahemmet University, Box 5606, 114 28, Stockholm, Sweden.
Per FranssonDepartment of Nursing, Umeå University, 901 87, Umeå, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundQuality of Life (QoL) is the most important outcome for patients in palliative care along with symptom alleviation. Metastatic prostate cancer (mPC) is a life-threatening illness, and hence, a palliative care approach may be beneficial to this group. Over time, new life-prolonging treatments have been developed for men with mPC, but the possibility to prolong life should also be balanced against the men's QoL, particularly because there are side effects involved with these treatments. The aim of this study was to evaluate QoL, functioning and symptoms in men with mPC during their final years before death.

methodsThis is a retrospective analysis of data from a long-term prospective study of men (n = 3885) with prostate cancer from two regions in Sweden. Validated questionnaires asking about participants' QoL, functioning and symptoms were used to collect data. From the overall study, 190 men with mPC were identified. They were stratified into three groups, depending on the amount of time that had passed between the last questionnaire and their death; < 6 months, 6-18 months and > 18 months before death.

resultsMen with mPC generally rated their QoL poorly compared to established clinically significant threshold values. The group of men that were < 6 months before death rated their QoL, functioning and several symptoms significantly worse than the two other groups. Men that died after the year 2006 reported lower QoL and functioning and more pain and fatigue than those who died before 2006.

conclusionThe results in this study indicate that men with mPC have unmet needs with regards to QoL and symptoms. A palliative care approach, alongside possible life-prolonging treatments, that focuses on QoL and symptom relief, may serve as an important frame to give the best support to these men in their final years of life.

Indexed as

Palliative CareAgedCancer PainFatigueHumansMaleNeeds AssessmentNeoplasm MetastasisProstatic NeoplasmsQuality of LifeRetrospective StudiesSwedenTerminally IllLife-prolonging treatmentMetastatic diseasePalliative careProstate cancerQuality of life

Identifiers

PMID30509249
PMCPMC6278096

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.