Evidence map›Paper›PMID 30508890›Full record

Trial reportMedicine2018

Computed tomography portography of patients with cirrhosis with normal body mass index: Comparison between low-tube-voltage CT with low contrast agent dose and conventional CT.

Sulan Liu, Huaqiang Sheng, Hao Shi, Wei Li, Jingli Fan, Jingzhen He, Hongjun Sun

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sulan LiuDepartment of Medical Imaging, Qianfoshan Hospital Affiliated to Shandong University.
Huaqiang ShengDepartment of Medical Imaging, Qianfoshan Hospital Affiliated to Shandong University.
Hao ShiDepartment of Medical Imaging, Qianfoshan Hospital Affiliated to Shandong University.
Wei LiDepartment of Medical Imaging, Qianfoshan Hospital Affiliated to Shandong University.
Jingli FanInstitute of Endemic Disease Prevention and Control of Shandong Province.
Jingzhen HeDepartment of Radiology, Qilu Hospital Affiliated to Shandong University, Jinan, China.
Hongjun SunDepartment of Medical Imaging, Qianfoshan Hospital Affiliated to Shandong University.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study is to investigate the computed tomography (CT) image quality of the low- tube-voltage protocol with low contrast agent dose.CT portography was performed in 118 cirrhosis patients with body mass index (BMI) less than 25 kg/m under 2 protocols: Protocol A, tube voltage of 90 kVp/395 mAs and contrast agent dosage of 1.2 mL/kg, and, Protocol B, tube voltage of 120 kVp/200 mAs and contrast agent dosage of 1.5 mL/kg.The number of patients in each protocol was 59. The CT value noise, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) in portal veins was comparatively analyzed between the 2 protocols. The subjective image quality was further assessed on 5-point scales. Radiation dose was also recorded and statistical analysis was performed.The CT value, CNR, and SNR of the images were higher at 90 kVp than those at 120 kVp (P < .05). There was no significant difference in image noise between the 2 protocols (P > .05). The CT dose index volume, dose-length product, and effective dose at 90 kVp were 18.2%, 16.0%, and 16.0% less than that at 120 kVp, respectively. There was no difference in image quality score between the 2 protocols (P > .05). The average amount of contrast agent was decreased by 17.8% when the 90 kVp protocol was used.CT portography at 90 kVp combined with low-dosage contrast agent leads to a significant reduction in radiation dose and improved SNR and CNR, without deterioration of image quality.

Indexed as

Body Mass IndexAdultAgedContrast MediaDose-Response Relationship, DrugFemaleHumansIohexolLiver CirrhosisMaleMiddle AgedPortographyRadiation DosageRadiographic Image Interpretation, Computer-AssistedTomography, X-Ray ComputedContrast MediaIohexol

Identifiers

PMID30508890
PMCPMC6283149

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.