Evidence map›Paper›PMID 30508658›Full record

ReviewCarbohydrate research2019

Recent advances in site-selective functionalization of carbohydrates mediated by organocatalysts.

Stephanie A Blaszczyk, Timothy C Homan, Weiping Tang

Abstract readReview
In one paragraph

Review in Carbohydrate research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Ferrocenium complex aidedRSC advances · 2021
    Article
  12. Review
  13. A Mechanistic Probe into 1,2-Advanced synthesis & catalysis · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Site-Selective and StereoselectiveJournal of the American Chemical Society · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Stephanie A BlaszczykSchool of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA.
Timothy C HomanChemistry Department, Grove City College, Grove City, PA, 16127, USA.
Weiping TangSchool of Pharmacy, University of Wisconsin-Madison, Madison, WI, 53705, USA; Department of Chemistry, University of Wisconsin-Madison, Madison, WI, 53706, USA. Electronic address: weiping.tang@wisc.edu.

Funding

Chemistry-Biology Interface Training ProgramT32GM008505 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI BLACKWELL, HELEN E. · 1993 to 2023
$9.8M
Develop Catalytic Methods to Streamline the Assembly of OligosaccharidesU01GM125290 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI TANG, WEIPING · 2017 to 2020
$2.2M
NIGMS NIH HHS T32 GM008505NIGMS NIH HHS U01 GM125290
6 · The paper itself

Abstract

As one of the four fundamental building blocks of life, carbohydrates assume varied and expansive roles in biological contexts. More in-depth understanding of carbohydrates and their interactions, however, is often restricted by our inability to synthesize and subsequently functionalize them in a site-selective manner. This review will summarize recent advances in the site-selective functionalization of carbohydrates using organocatalysts, including achiral catalysts, chiral nucleophilic bases, chiral N-heterocyclic carbenes, and chiral phosphoric acids, with an emphasis on the catalytic nature in each case. As in many endeavors, taking an alternative approach can often lead to success, and selected examples of these achievements will be highlighted as well.

Indexed as

CarbohydratesCatalysisMethaneMolecular StructurePhosphoric AcidsStereoisomerismcarbeneCarbohydratesMethanePhosphoric AcidsCarbohydrateOrganocatalysisSite-selective functionalization

Identifiers

PMID30508658
PMCPMC6743478

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.