Evidence map›Paper›PMID 30507789›Full record

ArticleJournal of occupational and environmental medicine2019

Can Blood Flow be Used to Monitor Changes in Peripheral Vascular Function That Occur in Response to Segmental Vibration Exposure?

Kristine Krajnak, Stacey Waugh, Khachatur Sarkisian

Open access · greenAbstract read
In one paragraph

Article in Journal of occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Kristine KrajnakEngineering Controls and Technology Branch (Dr Krajnak, Ms Waugh); Biostatistics and Epidemiology Branch (Mr Sarkisian), National Institute for Occupational Safety and Health, Morgantown, West Virginia.
Stacey Waugh
Khachatur Sarkisian
National Institute for Occupational Safety and Health · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

objectivesLaser Doppler blood flow measurements have been used for diagnosis or detection of peripheral vascular dysfunction. This study used a rat tail model of vibration-induced vascular injury to determine how laser Doppler measurements were affected by acute and repeated exposures to vibration, and to identify changes in the Doppler signal that were associated with the exposure.

methodsBlood flow was measured immediately after a single exposure to vibration, or before vibration exposure on days 1, 5, 10, 15, and 20 of a 20 days exposure.

resultsAfter a single exposure to vibration, average tail blood flow was reduced. With 20 days of exposure, there was a reduction in the amplitude of the arterial pulse on days 10 to 20 in vibrated rats and days 15 to 20 in control rats.

conclusionsMore detailed statistical analyses of laser Doppler data may be needed to identify early changes in peripheral circulation after exposure to vibration.

Indexed as

Monitoring, PhysiologicRegional Blood FlowAnimalsHumansMalePeripheral Vascular DiseasesRatsRats, Sprague-DawleyTime FactorsVibration

Identifiers

PMID30507789
PMCPMC6531854
OpenAlexW2902943175

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.