Evidence map›Paper›PMID 30507365›Full record

ArticleJournal of toxicology and environmental health. Part A2018

Exposure to mixtures of mercury, cadmium, lead, and arsenic alters the disposition of single metals in tissues of Wistar rats.

Sarah E Orr, Mary C Barnes, Hannah S George, Lucy Joshee, Byunggwon Jeon, Austin Scircle, Oscar Black, James V Cizdziel, Betsy E Smith, Christy C Bridges

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of toxicology and environmental health. Part A, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Evaluation of Fetal Exposures to Metals and Metalloids through Meconium Analyses: A Review.International journal of environmental research and public health · 2021
    Pooled it
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Sarah E Orra Department of Biomedical Sciences , Mercer University School of Medicine , Macon , GA , USA.
Mary C Barnesa Department of Biomedical Sciences , Mercer University School of Medicine , Macon , GA , USA.
Hannah S Georgea Department of Biomedical Sciences , Mercer University School of Medicine , Macon , GA , USA.
Lucy Josheea Department of Biomedical Sciences , Mercer University School of Medicine , Macon , GA , USA.
Byunggwon Jeonb Department of Chemistry and Biochemistry , University of Mississippi, University , MS , USA.
Austin Scircleb Department of Chemistry and Biochemistry , University of Mississippi, University , MS , USA.
Oscar Blackb Department of Chemistry and Biochemistry , University of Mississippi, University , MS , USA.
James V Cizdzielb Department of Chemistry and Biochemistry , University of Mississippi, University , MS , USA.
Betsy E Smithc Department of Internal Medicine , Mercer University School of Medicine , Macon , GA , USA.
Christy C Bridgesa Department of Biomedical Sciences , Mercer University School of Medicine , Macon , GA , USA.ORCID http://orcid.org/0000-0003-1603-1445
Mercer University · USUniversity of Mississippi · US

Funding

Proximal Tubular Transport of Mercury and Effects of Reduced Renal MassR15ES019991 · NIEHS · MERCER UNIVERSITY MACON · PI BRIDGES, CHRISTY C · 2011 to 2011
$471k
NIEHS NIH HHS R15 ES019991
6 · The paper itself

Abstract

Humans throughout the world are exposed regularly to mixtures of environmental toxicants. Four of the most common heavy metal toxicants in the environment are mercury (Hg), cadmium (Cd), lead (Pb), and arsenic (As). Numerous studies have assessed the effects and disposition of individual metals in organ systems; however, humans are usually exposed to mixtures of toxicants or metals rather than to a single toxicant. Therefore, the purpose of the current study was to test the hypothesis that exposure to a mixture of toxic heavy metals alters the disposition of single metals in target organs. Wistar rats (

Indexed as

arseniccadmiumleadMercurymixtures

Identifiers

PMID30507365
PMCPMC6546563
OpenAlexW2902142755

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.