ArticleJournal of medicinal chemistry2019
New Water-Soluble Copper(II) Complexes with Morpholine-Thiosemicarbazone Hybrids: Insights into the Anticancer and Antibacterial Mode of Action.
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Article in Journal of medicinal chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 1 of them a synthesis that pooled it.
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24citing papers in PubMed, 1 pooled it
4.2field-weighted citation impact, top 4% of its field
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Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 121 citations in OpenAlex.
- Potential Biological Targets of Anticancer Metal-Based Drug Candidates: A Systematic Review.Drug development research · 2026Pooled it
- Article
- Synthesis and Characterization of Copper(II) and Nickel(II) Complexes with 3-(Morpholin-4-yl)propane-2,3-dione 4-Allylthiosemicarbazone Exploring the Antibacterial, Antifungal and Antiradical Properties.Molecules (Basel, Switzerland) · 2024Article
- Crystal Structure, Theoretical Analysis, and Protein/DNA Binding Activity of Iron(III) Complex Containing Differently Protonated Pyridoxal-International journal of molecular sciences · 2024Article
- Copper(II) Complexes with Isomeric Morpholine-Substituted 2-Formylpyridine Thiosemicarbazone Hybrids as Potential Anticancer Drugs Inhibiting Both Ribonucleotide Reductase and Tubulin Polymerization: The Morpholine Position Matters.Journal of medicinal chemistry · 2024Article
- Ternary Phenolate-Based Thiosemicarbazone Complexes of Copper(II): Magnetostructural Properties, Spectroscopic Features and Marked Selective Antiproliferative Activity against Cancer Cells.Molecules (Basel, Switzerland) · 2024Article
- Combined In Silico and In Vitro Analyses to Assess the Anticancer Potential of Thiazolidinedione-Thiosemicarbazone Hybrid Molecules.International journal of molecular sciences · 2023Article
- Crystal Design, Antitumor Activity and Molecular Docking of Novel Palladium(II) and Gold(III) Complexes with a Thiosemicarbazone Ligand.International journal of molecular sciences · 2023Article
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- Exploring the Biological Properties of Zn(II)International journal of molecular sciences · 2023Article
- Design, synthesis and characterization of novel Ni(II) and Cu(II) complexes as antivirus drug candidates against SARS-CoV-2 and HIV virus.Journal of molecular structure · 2022Article
- Article
- Synthesis, Crystal Structure, Quantum Chemical Analysis, Electrochemical Behavior, and Antibacterial and Photocatalytic Activity of Co Complex with Pyridoxal-(S-Methyl)-isothiosemicarbazone Ligand.Molecules (Basel, Switzerland) · 2022Article
- Elucidation of Structure-Activity Relationships in Indolobenzazepine-Derived Ligands and Their Copper(II) Complexes: the Role of Key Structural Components and Insight into the Mechanism of Action.Inorganic chemistry · 2022Article
- Biological Properties of Transition Metal Complexes with Metformin and Its Analogues.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Highly Antiproliferative Latonduine and Indolo[2,3-Journal of medicinal chemistry · 2022Article
- Inhibition of Microtubule Dynamics in Cancer Cells by Indole-Modified Latonduine Derivatives and Their Metal Complexes.Inorganic chemistry · 2022Article
- Triapine Analogues and Their Copper(II) Complexes: Synthesis, Characterization, Solution Speciation, Redox Activity, Cytotoxicity, and mR2 RNR Inhibition.Inorganic chemistry · 2021Article
- Modulation of Intracellular Copper Levels as the Mechanism of Action of Anticancer Copper Complexes: Clinical Relevance.Biomedicines · 2021Review
- Coumarin-Based Triapine Derivatives and Their Copper(II) Complexes: Synthesis, Cytotoxicity and mR2 RNR Inhibition Activity.Biomolecules · 2021Article
Corrections and comments
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Authors and funding
17 authors at 8 institutions in 7 countries.
Kateryna OhuiInstitute of Inorganic Chemistry , University of Vienna , Währinger Strasse 42 , A-1090 Vienna , Austria.
Eleonora AfanasenkoInstitute of Inorganic Chemistry , University of Vienna , Währinger Strasse 42 , A-1090 Vienna , Austria.
Felix BacherInstitute of Inorganic Chemistry , University of Vienna , Währinger Strasse 42 , A-1090 Vienna , Austria.
Rachel Lim Xue TingDepartment of Pharmacy , National University of Singapore , 3 Science Drive 2 , Singapore 117543 , Singapore.
Ayesha ZafarSchool of Chemical Sciences , University of Auckland , Auckland 1010 , New Zealand.
Núria Blanco-CabraBacterial Infections: Antimicrobial Therapies, Institute for Bioengineering of Catalonia (IBEC) , The Barcelona Institute of Science and Technology , Barcelona 08036 , Spain.
Eduard TorrentsBacterial Infections: Antimicrobial Therapies, Institute for Bioengineering of Catalonia (IBEC) , The Barcelona Institute of Science and Technology , Barcelona 08036 , Spain.ORCID 0000-0002-3010-1609
Orsolya DömötörDepartment of Inorganic and Analytical Chemistry , University of Szeged , Dóm tér 7. , H-6720 Szeged , Hungary.
Nóra V MayResearch Centre of Natural Sciences , Hungarian Academy of Sciences , Magyar tudósok körútja 2. , H-1117 Budapest , Hungary.ORCID 0000-0003-4770-4681
Denisa DarvasiovaInstitute of Physical Chemistry and Chemical Physics , Slovak Technical University of Technology , Radlinského 9 , 81237 Bratislava , Slovak Republic.
Éva A EnyedyDepartment of Inorganic and Analytical Chemistry , University of Szeged , Dóm tér 7. , H-6720 Szeged , Hungary.
Ana Popović-BijelićFaculty of Physical Chemistry , University of Belgrade , 11158 Belgrade , Serbia.ORCID 0000-0003-3121-2391
Jóhannes ReynissonSchool of Chemical Sciences , University of Auckland , Auckland 1010 , New Zealand.
Peter RaptaInstitute of Physical Chemistry and Chemical Physics , Slovak Technical University of Technology , Radlinského 9 , 81237 Bratislava , Slovak Republic.
Maria V BabakDepartment of Chemistry , National University of Singapore , 3 Science Drive 2 , 117543 , Singapore.ORCID 0000-0002-2009-7837
Giorgia PastorinDepartment of Pharmacy , National University of Singapore , 3 Science Drive 2 , Singapore 117543 , Singapore.ORCID 0000-0002-2568-0626
Vladimir B ArionInstitute of Inorganic Chemistry , University of Vienna , Währinger Strasse 42 , A-1090 Vienna , Austria.ORCID 0000-0002-1895-6460
University of Vienna · ATNational University of Singapore · SGInstitute for Bioengineering of Catalonia · ESSlovak University of Technology in Bratislava · SKUniversity of Auckland · NZUniversity of Szeged · HUHUN-REN Research Centre for Natural Sciences · HUUniversity of Belgrade · RS
Funding
No grant is acknowledged in the PubMed record.
Abstract
Six morpholine-(iso)thiosemicarbazone hybrids HL
Indexed as
AnimalsAnti-Bacterial AgentsAntineoplastic AgentsBinding SitesCatalytic DomainCell Line, TumorCell ProliferationCoordination ComplexesCopperCrystallography, X-RayHumansMiceMolecular ConformationMolecular Docking SimulationMorpholinesOrphan Nuclear ReceptorsAnti-Bacterial AgentsAntineoplastic AgentsCoordination ComplexesCopperMorpholinesOrphan Nuclear ReceptorsThiosemicarbazones
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.