Evidence map›Paper›PMID 30507136›Full record

ArticleACS applied materials & interfaces2018

Integrating 3D Printing and Biomimetic Mineralization for Personalized Enhanced Osteogenesis, Angiogenesis, and Osteointegration.

Limin Ma, Xiaolan Wang, Naru Zhao, Ye Zhu, Zhiye Qiu, Qingtao Li, Ye Zhou, Zefeng Lin, Xiang Li, Xiaolong Zeng and 5 more

Abstract read
In one paragraph

Article in ACS applied materials & interfaces, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Consequences of Aging on Bone.Aging and disease · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Nano-Based 3D Printed Scaffold for Bone Tissue Engineering.Bioengineering (Basel, Switzerland) · 2026
    Review
  5. Article
  6. The Therapeutic Scope of Orofacial Mesenchymal Stem Cells.Bioengineering (Basel, Switzerland) · 2025
    Review
  7. Review
  8. Review
  9. Article
  10. [Research progress of bioactive scaffolds in repair and regeneration of osteoporotic bone defects].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2025
    Review
  11. Design of internal fixation implants for fracture: A review.Journal of orthopaedic translation · 2025
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Limin MaDepartment of Orthopedics , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , Guangdong 510080 , PR China.
Xiaolan WangDepartment of Orthopedics , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , Guangdong 510080 , PR China.
Naru ZhaoSchool of Materials Science and Engineering , South China University of Technology , Guangzhou , 510641 , PR China.
Ye ZhuDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, Institute for Biomedical Engineering, Science and Technology , University of Oklahoma , Norman , Oklahoma 73072 , United States.
Zhiye QiuInstitute for Regenerative Medicine and Biomimetic Materials , Tsinghua University , Beijing 100084 , PR China.
Qingtao LiSchool of Materials Science and Engineering , South China University of Technology , Guangzhou , 510641 , PR China.
Ye ZhouDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant , Guangzhou General Hospital of Guangzhou Military Command , Guangzhou , 510010 , PR China.
Zefeng LinDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant , Guangzhou General Hospital of Guangzhou Military Command , Guangzhou , 510010 , PR China.
Xiang LiSchool of Mechanical Engineering , Shanghai Jiao Tong University, State Key Laboratory of Mechanical System and Vibration , Shanghai 200240 , PR China.
Xiaolong ZengDepartment of Orthopedics , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , Guangdong 510080 , PR China.
Hong XiaDepartment of Orthopedics, Guangdong Key Lab of Orthopedic Technology and Implant , Guangzhou General Hospital of Guangzhou Military Command , Guangzhou , 510010 , PR China.
Shizhen ZhongSchool of Basic Medical Sciences , Southern Medical University , Guangzhou 510515 , PR China.
Yu ZhangDepartment of Orthopedics , Guangdong General Hospital, Guangdong Academy of Medical Sciences , Guangzhou , Guangdong 510080 , PR China.
Yingjun WangSchool of Materials Science and Engineering , South China University of Technology , Guangzhou , 510641 , PR China.
Chuanbin MaoDepartment of Chemistry and Biochemistry, Stephenson Life Sciences Research Center, Institute for Biomedical Engineering, Science and Technology , University of Oklahoma , Norman , Oklahoma 73072 , United States.ORCID http://orcid.org/0000-0002-8142-3659

Funding

Virus-based nanoparticles for detecting breast cancer biomarkersR01EB021339 · NIBIB · UNIVERSITY OF OKLAHOMA · PI CAO, BINRUI · 2016 to 2019
$1.4M
NIBIB NIH HHS R01 EB021339
6 · The paper itself

Abstract

Titanium (Ti) alloy implants can repair bone defects at load-bearing sites. However, they mechanically mismatch with the natural bone and lack customized adaption with the irregularly major-sized load-bearing bone defects, resulting in the failure of implant fixation. Mineralized collagen (MC), a building block in bone, can induce angiogenesis and osteogenesis, and 3D printing technology can be employed to prepare scaffolds with an overall shape customized to the bone defect. Hence, we induced the formation of MC, made of hydroxyapatite (HAp) nanocrystals and collagen fibers, in 3D-printed porous Ti

Indexed as

Biocompatible MaterialsBiomimetic MaterialsPrinting, Three-DimensionalRadius FracturesAlloysAnimalsCalcification, PhysiologicFemaleMaleNeovascularization, PhysiologicOsseointegrationOsteogenesisPorosityRabbitsTissue ScaffoldsTitaniumAlloysBiocompatible MaterialsTitaniumtitanium alloy (TiAl6V4)angiogenesismineralized collagenosteogenesisosteointegrationporous titanium alloys

Identifiers

PMID30507136
PMCPMC6456406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.