Evidence map›Paper›PMID 30506967›Full record

ArticleExperimental dermatology2019

Ultraviolet radiation, both UVA and UVB, influences the composition of the skin microbiome.

Erin M Burns, Hana Ahmed, Prescilia N Isedeh, Indermeet Kohli, William Van Der Pol, Abdullah Shaheen, Anum F Muzaffar, Camli Al-Sadek, Thompson M Foy, Mohammad S Abdelgawwad and 7 more

Abstract read
In one paragraph

Article in Experimental dermatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.

0numbers the graph read from it
0cells of the map it votes in
59citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

59 citing papers in PubMed.

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  19. Vitiligo: are microbes to blame?Bioscience of microbiota, food and health · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Erin M BurnsDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Hana AhmedCollege of Medicine, Florida State University, Tallahassee, Florida.
Prescilia N IsedehDepartment of Dermatology, Henry Ford Hospital, Detroit, Michigan.
Indermeet KohliDepartment of Dermatology, Henry Ford Hospital, Detroit, Michigan.
William Van Der PolCenter for Clinical and Translational Science, UAB, Birmingham, Alabama.
Abdullah ShaheenDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Anum F MuzaffarDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Camli Al-SadekDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Thompson M FoyDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Mohammad S AbdelgawwadDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Sumeira HudaDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Henry W LimDepartment of Dermatology, Henry Ford Hospital, Detroit, Michigan.
Iltefat HamzaviDepartment of Dermatology, Henry Ford Hospital, Detroit, Michigan.
Sejong BaeDivision of Preventive Medicine, UAB, Birmingham, Alabama.
Casey D MorrowDepartment of Cell, Developmental, and Integrative Biology, UAB, Birmingham, Alabama.
Craig A ElmetsDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.
Nabiha YusufDepartment of Dermatology, University of Alabama at Birmingham (UAB), Birmingham, Alabama.ORCID 0000-0001-5730-0037

Funding

XRAY CRYSTALLOGRAPHYP30CA013148 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Robert S Welner · 1985 to 2026
$165.9M
UAB Center for Clinical and Translational Science (CCTS)UL1TR001417 · NCATS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI KIMBERLY, ROBERT P. · 2015 to 2018
$31.4M
UAB Skin Diseases Research CenterP30AR050948 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ELMETS, CRAIG A · 2004 to 2013
$5.5M
Mechanisms elicited by type I interferons in cutaneous photocarcinogenesisR01AR071157 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI YUSUF, NABIHA · 2016 to 2020
$1.8M
NCATS NIH HHS UL1 TR001417NCI NIH HHS P30 CA013148NIAMS NIH HHS 1R01AR071157-01A1NIAMS NIH HHS P30 AR050948NIAMS NIH HHS R01 AR071157NIHNIH Cancer Prevention and Control Training Grant R25 CA47888University of Alabama at Birmingham
6 · The paper itself

Abstract

backgroundStudies have begun to investigate the complex relationship between host and microorganisms in non-infectious pathologies such as acne, atopic dermatitis and psoriasis. Though the skin is exposed to environmental stressors such as ultraviolet radiation (UVR), no studies exist examining the effects of both UVA and UVB on the skin microbiome.

objectiveTo test the effect of UVA and UVB on human skin microbiome.

methodsTo test whether UV will alter the cutaneous microbiome, participants were exposed to doses of UVA (22-47 J/cm

resultsThere was vast intra- and inter-subject variation at all time points, and phylum and species-level differences were identified. These included an increase in the phylum Cyanobacteria and a decrease in the family Lactobacillaceae and Pseudomonadaceae. The sensitivity of microbes to UVR and their re-colonization potential following exposure differed in UVA vs UVB samples. LIMITATIONS: The sample size was small, and the study was limited to males.

conclusionThe results demonstrate that UVR has profound qualitative and quantitative influences on the composition of the skin microbiome, possibly effecting skin pathology in which UVR is a factor.

Indexed as

Ultraviolet RaysAcne VulgarisAdultDermatitis, AtopicDNAHumansInflammationMaleMicrobiotaPsoriasisSkinYoung AdultDNAmicrobiomeskinultraviolet radiation

Identifiers

PMID30506967
PMCPMC7394481

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.