Evidence map›Paper›PMID 30506746›Full record

ArticleJournal of veterinary internal medicine2019

Relationships among urinary protein-to-creatinine ratio, urine specific gravity, and bacteriuria in canine urine samples.

Alison G Meindl, Bianca N Lourenço, Amanda E Coleman, Kate E Creevy

Abstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
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  6. Influence of preanalytic and analytic variables in canine and feline urine specific gravity measurement by refractometer.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2020
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  10. Article
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  12. Article
  13. Evaluation of a rapid immunoassay for bacteriuria in dogs.Journal of veterinary internal medicine
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alison G MeindlDepartment of Small Animal Medicine and Surgery, University of Georgia College of Veterinary Medicine, Athens, Georgia.ORCID https://orcid.org/0000-0002-4592-8158
Bianca N LourençoDepartment of Small Animal Medicine and Surgery, University of Georgia College of Veterinary Medicine, Athens, Georgia.ORCID https://orcid.org/0000-0001-5249-4645
Amanda E ColemanDepartment of Small Animal Medicine and Surgery, University of Georgia College of Veterinary Medicine, Athens, Georgia.ORCID https://orcid.org/0000-0001-5476-5963
Kate E CreevyDepartment of Small Animal Medicine and Surgery, University of Georgia College of Veterinary Medicine, Athens, Georgia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundProteinuria is a marker of chronic kidney disease in dogs and a risk factor for increased morbidity and death. Predictive models using the results of readily available screening tests could foster early recognition.

objectiveTo determine whether urine specific gravity (USG) and semiquantitative category of dipstick protein can be used to predict urinary protein-to-creatinine ratio (UP : C) and to examine the effect of urine culture results on UP : C in dogs. ANIMALS: Three hundred ninety-four dogs (482 visits) presented to a university Community Practice Clinic or Veterinary Teaching Hospital between January 2011 and November 2015.

methodsRetrospective study. Medical records were searched to identify dogs for which urinalysis, UP : C measurement, and urine culture testing were performed during a single hospital visit. Urine specific gravity, UP : C, dipstick protein concentration, and findings of urine sediment analysis and urine culture were recorded. Regression or Spearman correlation analysis was used to test for relationships between UP : C and USG within dipstick categories and between UP : C and bacterial colony-forming units per milliliter, respectively. Cohen's kappa test was used to evaluate agreement between urine culture and UP : C testing.

resultsThere were significant (P < .05) weak negative correlations (R CONCLUSIONS AND CLINICAL IMPORTANCE: Within dipstick protein categories, UP : C cannot be accurately predicted from USG. Repeating UP : C measurement after resolution of urinary tract infection is advisable.

Indexed as

AnimalsBacteriuriaCreatinineDog DiseasesDogsFemaleMaleProteinuriaRetrospective StudiesSpecific GravityUrinalysisCreatininedogproteinuriaurinalysisurinary tract infection

Identifiers

PMID30506746
PMCPMC6335512

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.