ArticleJournal of child psychology and psychiatry, and allied disciplines2019
The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder.
Article in Journal of child psychology and psychiatry, and allied disciplines, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- The p Factor Consistently Predicts Long-Term Psychiatric and Functional Outcomes in Anxiety-Disordered Youth.Journal of the American Academy of Child and Adolescent Psychiatry · 2021Trial
- Mid-childhood developmental and behavioural outcomes in infants with a family history of autism and/or attention deficit hyperactivity disorder.Journal of child psychology and psychiatry, and allied disciplines · 2026Article
- Where do neurodevelopmental conditions fit in transdiagnostic psychiatric frameworks? Incorporating a new neurodevelopmental spectrum.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2024Article
- Using the Infant Sibling-Design to Explore Associations Between Autism and ADHD Traits in Probands and Temperament in the Younger Siblings.Journal of autism and developmental disorders · 2024Article
- Social-Emotional Profiles of Preschool Children: An Investigation of Demographic Disparities and Intersectionality.International journal of environmental research and public health · 2024Article
- Unpacking the p-factor. Associations Between Maladaptive Personality Traits and General Psychopathology in Female and Male Adolescents.Research on child and adolescent psychopathology · 2024Article
- Identify adolescents' help-seeking intention on suicide through self- and caregiver's assessments of psychobehavioral problems: deep clustering of the Tokyo TEEN Cohort study.The Lancet regional health. Western Pacific · 2024Article
- Three year outcomes in infants with a family history of autism and/or attention deficit hyperactivity disorder.JCPP advances · 2023Article
- A longitudinal comparison of emotional, behavioral and attention problems in autistic and typically developing children.Psychological medicine · 2023Article
- Trajectories of dysregulation in preschool age.European child & adolescent psychiatry · 2022Article
- Shared and distinct developmental pathways to ASD and ADHD phenotypes among infants at familial risk.Development and psychopathology · 2020Article
- Perspectives on cross-diagnostic trajectories and outcomes in children's mental health.European child & adolescent psychiatry · 2020Article
Corrections and comments
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Authors and funding
7 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundThe 'dysregulation profile' (DP) is a measure of emotional and behavioral dysregulation that may cut across diagnostic boundaries. Siblings of children with autism spectrum disorder (ASD) who do not develop ASD themselves are at risk for atypical outcomes including behavioral challenges and therefore may be a useful population in which to investigate the structure of the DP in preschoolers.
methodsWe sought to examine the factor structure and predictors of the DP in a sample enriched for a wide range of phenotypic variation-36-month-olds with and without family histories of ASD-and to determine whether children with genetic liability for ASD are at risk for a phenotype characterized by elevated dysregulation. Data were collected from 415 children with (n = 253) and without (n = 162) an older sibling with ASD, all without ASD themselves, at 18, 24, and 36 months of age.
resultsOur findings replicate prior reports, conducted in predominantly clinically referred and older samples, supporting the superiority of a bifactor model of the DP in the preschool period compared to the second-order and one-factor models. Examiner ratings were longitudinally and concurrently associated with the DP at 36 months of age. Family history of ASD was associated with higher dysregulation in the Anxious/Depressed dimension.
conclusionsThese findings support the relevance of examining the structure of psychopathology in preschoolers and suggest that examiner observations as early as 18 months of age, particularly of overactivity, may help identify risk for later DP-related concerns. Non-ASD preschoolers with family histories of ASD may be at risk for a phenotype characterized by elevated dysregulation particularly in the Anxious/Depressed dimension by age 3.
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