ArticleFish physiology and biochemistry2019
In situ localization of vasotocin receptor gene transcripts in the brain-pituitary-gonadal axis of the catfish Heteropneustes fossilis: a morpho-functional study.
Article in Fish physiology and biochemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 17 citations in OpenAlex.
- Nonapeptide molecular evolution during the adaptive radiation of Tanganyika cichlids.Journal of neuroendocrinology · 2026Article
- Acute administration of Manning compound during the spawning period reduces reproductive success in female zebrafish.Frontiers in endocrinology · 2026Article
- Integrated Role of Arginine Vasotocin in the Control of Spermatogenesis in Zebrafish.International journal of molecular sciences · 2025Article
- The Role of Neurohypophysial Hormones in the Endocrine and Paracrine Control of Gametogenesis in Fish.Cells · 2025Review
- Arginine vasotocin is a player in the multifactorial control of spermatogenesis in zebrafish.Frontiers in endocrinology · 2025Article
- Arginine Vasotocin Directly Regulates Spermatogenesis in Adult Zebrafish (International journal of molecular sciences · 2024Article
- Neurohypophysial and paracrine vasopressinergic signaling regulates aquaporin trafficking to hydrate marine teleost oocytes.Frontiers in endocrinology · 2023Article
- Air sac and gill vasotocin receptor gene expression in the air-breathing catfish Heteropneustes fossilis exposed to water and air deprivation conditions.Fish physiology and biochemistry · 2022Article
- Reproductive roles of the vasopressin/oxytocin neuropeptide family in teleost fishes.Frontiers in endocrinology · 2022Review
- Neuroendocrine Regulation of Plasma Cortisol Levels During Smoltification and Seawater Acclimation of Atlantic Salmon.Frontiers in endocrinology · 2022Article
- Article
- The regulation of oocyte maturation and ovulation in the closest sister group of vertebrates.eLife · 2019Article
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3 authors at 2 institutions in 1 country.
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Abstract
In the catfish Heteropneustes fossilis, three vasotocin (VT) receptor subtype genes, v1a1, v1a2, and v2a, were cloned and characterized previously. In the present study, using RNA probes, we localized the distribution of the gene transcripts in the brain-pituitary-gonadal (BPG) axis. The V1a-type receptor, v1a1 and v1a2, genes showed similar and overlapping distribution in the brain. The gene paralogs are distributed in the radial glial cells (RGCs) of the telencephalic ventricle and around the third ventricle in the hypothalamus and thalamus, olfactory tract, nucleus preopticus, nucleus lateralis tuberis, nucleus recessus lateralis and posterioris, nucleus saccus vasculosi, thalamic nuclei, habenular nucleus, habenular commissure, basal part of pineal stalk, accessory pretectal nucleus, optic tectum, corpus and valvula of the cerebellum, and facial and vagal lobes. The V2a receptor gene (v2a) has restricted distribution and is largely confined to the anterior subependymal region of the telencephalon. The localization pattern shows that the V1a-type receptors are distributed in major sensorimotor processing centers and the neuroendocrine/reproductive centers of the brain. In the pituitary, the receptor genes were localized differentially in the three divisions with the V1a-type receptor genes strongly expressed in the rostral pars distalis compared to the v2a paralog. In the ovary, the V1a-type receptor genes were localized in the follicular layer while v2a was localized in the oocyte membrane. In the testis, v1a2 and v2a are densely distributed in the interstitial tissue and seminiferous epithelium but the v1a1 is lowly expressed. The results suggest that the VT receptor genes have an extensive but differential distribution in the BPG axis. Future experimental studies are required to correlate the cellular localizations with specific functions of VT in the BPG axis.
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