Evidence map›Paper›PMID 30506409›Full record

ArticleEnvironmental science and pollution research international2019

Cytotoxic and genotoxic effect of oxyfluorfen on hemocytes of Biomphalaria glabrata.

Maíra de Vasconcelos Lima, Williams Nascimento de Siqueira, Hianna Arely Milca Fagundes Silva, José de Melo Lima Filho, Elvis Joacir de França, Ana Maria Mendonça de Albuquerque Melo

Abstract read
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In one paragraph

Article in Environmental science and pollution research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Acute liver injury associated with Oxyfluorfen toxicity.SAGE open medical case reports · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Maíra de Vasconcelos LimaDepartamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Williams Nascimento de SiqueiraDepartamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil. williams.wns@gmail.com.ORCID http://orcid.org/0000-0001-6073-5875
Hianna Arely Milca Fagundes SilvaDepartamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
José de Melo Lima FilhoGrupo de Dosimetria Numérica, Instituto Federal de Educação Ciência e Tecnologia de Pernambuco, Recife, Pernambuco, 50740-540, Brazil.
Elvis Joacir de FrançaServiço de Monitoração Ambiental, Centro Regional de Ciências Nucleares do Nordeste, Recife, Pernambuco, 50740-545, Brazil.
Ana Maria Mendonça de Albuquerque MeloDepartamento de Biofísica e Radiobiologia, Universidade Federal de Pernambuco, Recife, Pernambuco, 50670-420, Brazil.
Universidade Federal de Pernambuco · BRCentro de Tecnologias Estratégicas do Nordeste · BRInstituto Federal de Educação, Ciência e Tecnologia de Pernambuco · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemicals released from anthropogenic activities such as industry and agriculture often end up in aquatic ecosystems. These substances can cause serious damage to these ecosystems, thus threatening the conservation of biodiversity. Among these substances are pesticides, such as oxyfluorfen, a herbicide used for the control of grasses and weeds. Considering its widespread use, it is important to investigate the possible toxicity of this compound to aquatic organisms, especially invertebrates. Hence, the use of biological systems able to detect such effects is of great importance. The mollusk Biomphalaria glabrata has been shown to be useful as an environmental indicator to assess the potential ecological effects of physical and chemical stressors in freshwater environments. The present study sought to detect mutagenic changes in hemocytes of B. glabrata exposed to oxyfluorfen. To perform these tests, this study used ten animals per group, exposed acutely (48 h) and chronically (15 days) to oxyfluorfen. The herbicide concentrations were 0.125, 0.25, and 0.5 mg/L. The results showed that oxyfluorfen induced significant frequencies of micronuclei, binucleated cells, and apoptosis in hemocytes of mollusks when compared to the control group. Unlike chronic exposure, acute exposure was dose-dependent. The present study's results demonstrate the cytotoxic and genotoxic effects of oxyfluorfen on hemocytes of B. glabrata.

Indexed as

AnimalsApoptosisBiomphalariaDose-Response Relationship, DrugHalogenated Diphenyl EthersHemocytesMicronuclei, Chromosome-DefectiveWater Pollutants, ChemicalHalogenated Diphenyl EthersoxyfluorofenWater Pollutants, ChemicalBiomphalaria glabrataGenotoxicHemocyteHerbicideMolluskOxyfluorfen

Identifiers

PMID30506409
OpenAlexW2902353800

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.