Evidence map›Paper›PMID 30506346›Full record

ArticleIrish journal of medical science2019

Gender impact on the correlations between Graves' hyperthyroidism and hyperuricemia in Chinese.

Xuehui Liu, Jianping Zhang, Zhaowei Meng, Qiang Jia, Jian Tan, Guizhi Zhang, Xue Li, Na Liu, Tianpeng Hu, Pingping Zhou and 3 more

Abstract read
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In one paragraph

Article in Irish journal of medical science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Uric Acid Metabolic Disorders in Pituitary-Target Gland Axis.Diabetes, metabolic syndrome and obesity : targets and therapy · 2024
    Review
  5. Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Xuehui LiuDepartment of Nuclear Medicine, Third Central Hospital of Tianjin, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Jintang Road No. 83, Hedong District, Tianjin, 300170, People's Republic of China.
Jianping ZhangDepartment of Nuclear Medicine, Third Central Hospital of Tianjin, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Jintang Road No. 83, Hedong District, Tianjin, 300170, People's Republic of China.
Zhaowei MengDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, People's Republic of China. jamesmencius@163.com.
Qiang JiaDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, People's Republic of China.
Jian TanDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, People's Republic of China.
Guizhi ZhangDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, People's Republic of China.
Xue LiDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, People's Republic of China.
Na LiuDepartment of Nuclear Medicine, Third Central Hospital of Tianjin, Tianjin Institute of Hepatobiliary Disease, Tianjin Key Laboratory of Artificial Cell, Artificial Cell Engineering Technology Research Center of Public Health Ministry, Jintang Road No. 83, Hedong District, Tianjin, 300170, People's Republic of China.
Tianpeng HuDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, People's Republic of China.
Pingping ZhouDepartment of Nuclear Medicine, Tianjin Medical University General Hospital, Anshan Road No. 154, Heping District, Tianjin, 300052, People's Republic of China.
Qing ZhangDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Kun SongDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Qiyu JiaDepartment of Health Management, Tianjin Medical University General Hospital, Tianjin, People's Republic of China.
Tianjin Medical University General Hospital · CNTianjin Medical University · CNTianjin Third Central Hospital · CN

Funding

Key Project of Tianjin Science and Technology Committee Foundation 16JCZDJC34300National Natural Science Foundation of China 81571709Tianjin Science and Technology Committee 11ZCGYSY05700Tianjin Science and Technology Committee 12ZCZDSY20400Tianjin Science and Technology Committee 13ZCZDSY20200
6 · The paper itself

Abstract

objectiveAn increased level of serum uric acid (SUA) can be observed in patients with hypothyroidism. Nonetheless, data on the relationship between hyperuricemia and hyperthyroidism was still controversial. Thus, we aimed to analyze the association between Graves' hyperthyroidism and hyperuricemia in Chinese men and women.

methodsWe recruited 103 male and 254 female patients with Graves' hyperthyroidism, as well as the same number of control subjects. Anthropometric measurements and fasting blood tests were collected and analyzed statistically by binary logistic regressions to determine the risk of developing hyperuricemia in hyperthyroidism.

resultsSUA levels in males were significantly higher than that in females in both patients and controls. SUA levels were also significantly increased in hyperthyroid patients compared to in controls in both genders. The incidence of hyperuricemia rose significantly in subjects with hyperthyroidism with a higher prevalence in males than in females. SUA was negatively correlated with age and fasting glucose in male hyperthyroid patients, while it was positively correlated with body height, body weight, free triiodothyronine, and free thyroxine in female patients. Hyperthyroidism was a risk factor for hyperuricemia with an odd ratio of 4.536 for men and 2.730 for women.

conclusionsFor hyperuricemia, hyperthyroidism was an important risk factor that should not be neglected, especially for men.

Indexed as

AdolescentAdultAgedAsian PeopleFemaleGender IdentityGraves DiseaseHumansHyperthyroidismHyperuricemiaMaleMiddle AgedRisk FactorsUric AcidYoung AdultUric AcidGenderGraves’ disease (GD)HyperthyroidismHyperuricemiaSerum uric acid (SUA)

Identifiers

PMID30506346
OpenAlexW2902316073

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.