SynthesisEuropean radiology2019
Age assessment by Demirjian's development stages of the third molar: a systematic review.
Synthesis in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Evidence of Age Estimation Procedures in Forensic Dentistry: Results from an Umbrella Review.Medicina (Kaunas, Lithuania) · 2023Pooled it
- How old are you? A systematic review investigating the relationship between age and mandibular third molar maturity.PloS one · 2023Pooled it
- The influence of adjacent anatomical context in tooth staging: observational study of non-cropped vs. cropped radiographs for dental age estimation.International journal of legal medicine · 2026Observational
- Comparing an Indian dataset with BioAlder using Demirjian's staging of the third molar.International journal of legal medicine · 2026Article
- The temporal course of third molar mineralization in a black South African population.International journal of legal medicine · 2026Article
- Evaluation of Demirjian staging method reproducibility and reliability for dental age estimation between eight forensic experts.International journal of legal medicine · 2025Article
- Radiologic assessment of third molar development and cervical vertebral maturation to validate age of majority in a Mexican population.International journal of legal medicine · 2025Article
- Comparison of original and new South African formulae for age estimation in African Black and white children and adolescents using dental and hand-wrist methods.International journal of legal medicine · 2025Article
- A probability model for estimating age in young individuals relative to key legal thresholds: 15, 18 or 21-year.International journal of legal medicine · 2025Article
- Influence of linear and angular parameters on lower third molar retention: the role of space allocation and transpalatal width.Frontiers in oral health · 2025Article
- Forensic Age Estimation: A Multifactorial Approach in a Retrospective Population Study.Diagnostics (Basel, Switzerland) · 2023Article
- Accuracy of different dental age estimation methods for determining the legal majority of 18 years in the Turkish population.Clinical oral investigations · 2022Article
- The impact of age mimicry bias on the accuracy of methods for age estimation based on Kvaal's pulp/tooth ratios: a bootstrap study.International journal of legal medicine · 2022Article
- Comparison of the third molar maturity index (IInternational journal of legal medicine · 2021Article
- Study of the ethnicity's influence on the third molar maturity index (IInternational journal of legal medicine · 2021Article
- A new model of classification of third molars development and its correlation with chronological age in a Brazilian subpopulation.International journal of legal medicine · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesRadiographic evaluation of the wisdom teeth (third molar) formation is a widely used age assessment method for adolescents and young adults. This systematic review examines evidence on the agreement between Demirjian's development stages of the third molar and chronological age.
methodsWe searched four databases up until May 2016 for studies reporting Demirjian's stages of third molar and confirmed chronological age of healthy individuals aged 10-25 years. Heterogeneity test of the included studies was performed.
resultsWe included 21 studies from all continents except Australia, all published after 2005. The mean chronological age for Demirjian's stages varied considerably between studies. The results from most studies were affected by age mimicry bias. Only a few of the studies based their results on an unbiased age structure, which we argue as important to provide an adequate description of the method's ability to estimate age.
conclusionObserved study variation in the timing of Demirjian's development stages for third molars has often been interpreted as differences between populations and ethnicities. However, we consider age mimicry to be a dominant bias in these studies. Hence, the scientific evidence is insufficient to conclude whether such differences exist. KEY POINTS: • There is significant heterogeneity between studies evaluating age assessment by Demirjian's third molar development. • Most of the studies were subject to the selection bias age mimicry which can be a source of heterogeneity. • Presence of age mimicry bias makes it impossible to compare and combine results. These biased studies should not be applied as reference studies for age assessment.
Indexed as
Identifiers
30506219What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.