Evidence map›Paper›PMID 30506217›Full record

ArticleEuropean radiology2019

Reducing both radiation and contrast doses in coronary CT angiography in lean patients on a 16-cm wide-detector CT using 70 kVp and ASiR-V algorithm, in comparison with the conventional 100-kVp protocol.

Yuhuan Chen, Zhentang Liu, Michelle Li, Yong Yu, Yongjun Jia, Guangming Ma, Zhijun Hu, DongHong Wei, Dou Li, Taiping He

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 39 citations in OpenAlex.

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  13. [Clinical Application of "Three-Low" Technique Combined with Artificial Intelligence Iterative Reconstruction Algorithm in Aortic CT Angiography].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2022
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  18. A comprehensive review of imaging findings in COVID-19 - status in early 2021.European journal of nuclear medicine and molecular imaging · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Yuhuan ChenShaanxi University of Chinese Medicine, Xianyang, 712000, China.
Zhentang LiuDepartment of Radiology, Chang'an Hospital, Xi'an, 710018, Shaanxi, China.
Michelle Li, Brookfield, USA.
Yong YuDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, 712000, China.
Yongjun JiaDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, 712000, China.
Guangming MaDepartment of Radiology, Affiliated Hospital of Shaanxi University of Chinese Medicine, Xianyang, 712000, China.
Zhijun HuDepartment of Radiology, Chang'an Hospital, Xi'an, 710018, Shaanxi, China.
DongHong WeiDepartment of Radiology, Chang'an Hospital, Xi'an, 710018, Shaanxi, China.
Dou LiDepartment of Radiology, Chang'an Hospital, Xi'an, 710018, Shaanxi, China.
Taiping HeShaanxi University of Chinese Medicine, Xianyang, 712000, China. htpkeyan@163.com.ORCID http://orcid.org/0000-0002-3100-8086
Affiliated Hospital of Shaanxi University of Chinese Medicine · CNChicago Zoological Society · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the value of prospectively ECG-triggered coronary CT angiography (CCTA) for lean patients with body mass index (BMI) ≤ 23 kg/m MATERIALS AND

methodsThirty patients (group A) were prospectively enrolled to undergo 70-kVp CCTA on a 16-cm wide-detector CT scanner with noise index (NI) of 36 HU and at weight-dependent contrast dose rate of 16 mg I/kg/s for 9-s injection. Images were reconstructed with 80% ASiR-V. Radiation dose, contrast dose, and image quality were statistically compared with 30 patients (group B) in database with matching BMI who underwent conventional 100-kVp CCTA with NI of 25 HU, and at 25 mg I/kg/s rate for 10-s injection and reconstructed with 60% ASiR-V.

resultsThere was no significant difference in patient demographics between the two groups (all p > 0.05). The two groups also had similar mean CT values and contrast-noise ratio (CNR) and subjective image quality (all p > 0.05). However, group A with 70 kVp reduced the effective dose by 75.3% compared with group B (0.43 ± 0.20 mSv vs. 1.74 ± 1.01 mSv, p < 0.001), and required 42.4% less contrast dose than group B (22.46 ± 2.94 ml vs. 38.99 ± 5.10 ml, p < 0.001).

conclusionsProspectively ECG-triggered CCTA using 70 kVp and high-level ASiR-V on a 16-cm wide-detector CT system provides diagnostic images with substantial reduction in both radiation and contrast doses for patients with BMI ≤ 23 kg/m KEY POINTS: • 70-kVp CCTA produces excellent images at sub-millisievert radiation. • 70-kVp CCTA reduces both radiation and contrast doses over conventional protocol. • Achieving low-dose CCTA with combined low kVp and high-level ASIR-V.

Indexed as

AdultAgedAlgorithmsBody Mass IndexClinical ProtocolsComputed Tomography AngiographyContrast MediaCoronary AngiographyElectrocardiographyFemaleHumansMaleMiddle AgedProspective StudiesRadiation DosageRadiographic Image Interpretation, Computer-AssistedContrast MediaComputed tomography angiographyContrast mediaCoronary angiographyRadiation dosage

Identifiers

PMID30506217
OpenAlexW2903479603

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.