Evidence map›Paper›PMID 30506182›Full record

ArticleInternational urogynecology journal2019

Prospective evaluation of paravaginal defect repair with and without apical suspension: a 6-month postoperative follow-up with MRI, clinical examination, and questionnaires.

Louise T S Arenholt, Bodil Ginnerup Pedersen, Karin Glavind, Susanne Greisen, Karl M Bek, Marianne Glavind-Kristensen

Registry-linked trialAbstract read
PubMed Publisher
In one paragraph

Article in International urogynecology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05602246 (Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05602246 narecruitingnot on this mapstarted 2022, after this paper: background citation

Study Comparing Transobturator Cystocele vs. Anterior Vaginal RepairS

TypeinterventionalSponsorCharles University, Czech RepublicRan2022 to 2034Enrolled592ConditionsPelvic Organ Prolapse, Cystocele, Cystocele and Incomplete Uterovaginal ProlapseArmsTransobturator cystocele repair, Anterior colporrhaphy
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Trans-obturator cystocele repair of level 2 paravaginal defect.International urogynecology journal · 2020
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Louise T S ArenholtCentre for Clinical Research, Department of Obstetrics and Gynaecology, North Denmark Regional Hospital, Bispensgade 37, 9800, Hjoerring, Denmark. LTSA@RN.DK.ORCID 0000-0002-8403-8641
Bodil Ginnerup PedersenDepartment of Radiology, Aarhus University Hospital, Aarhus, Denmark.
Karin GlavindDepartment of Obstetrics and Gynaecology, Aalborg University Hospital, Aalborg, Denmark.
Susanne GreisenDepartment of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.
Karl M BekDepartment of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.
Marianne Glavind-KristensenDepartment of Obstetrics and Gynaecology, Aarhus University Hospital, Aarhus, Denmark.
Aarhus University Hospital · DKAalborg University Hospital · DKNorth Denmark Region · DK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introduction and hypothesisParavaginal defect (PVD) has been suggested as one of the main contributors to the development of prolapse in the anterior vaginal wall (AVW). We aimed to evaluate the descent of pelvic organs, presence of vaginal H configuration, and pubococcygeus (PC) muscle defect by pelvic magnetic resonance imaging (MRI), together with subjective symptoms of prolapse, before and 6 months after PVD repair. We also aimed to evaluate risk factors of recurrence.

methodsFifty women with PVD diagnosed by gynecological examination and scheduled for vaginal PVD repair were planned for enrollment. Preoperatively and 6 months postoperatively, subjective symptoms were evaluated using the International Consultation on Incontinence Questionnaire-Vaginal Symptoms (ICIQ-VS) together with MRI of the pelvis to evaluate defects in the PC muscle, vaginal shape, and pelvic organ descent.

resultsForty-six women completed the study. Twenty had PVD repair alone, whereas 26 also had concomitant surgery performed. Prolapse grade, subjective symptoms, sexual problems, and quality of life (QoL) were significantly improved at follow-up. Missing vaginal H configuration was observed in 21 women before operation and was correlated with PC muscle defect. Recurrence rate was 39%, and significantly more women with recurrence had PC muscle defects and missing H configuration.

conclusionVaginal PVD repair alone or combined with concomitant surgery significantly reduces objective prolapse and subjective symptoms. We could not demonstrate MRI findings of missing H configuration to be a sign of PVD but, rather, a sign of defect in the PC muscle. Risk of recurrence is significantly higher in women with major PC muscle defects and missing H configuration.

Indexed as

AdultAgedFemaleFollow-Up StudiesGynecologic Surgical ProceduresHumansMagnetic Resonance ImagingMiddle AgedPelvic Organ ProlapseProspective StudiesRecurrenceSurveys and QuestionnairesVaginaLevator ani defectsMRIParavaginal defectParavaginal defect repairPubococcygeus defectPVD

Identifiers

PMID30506182
OpenAlexW2902846291

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.