ReviewWorld journal of otorhinolaryngology - head and neck surgery2018
The microbiome and chronic rhinosinusitis.
Review in World journal of otorhinolaryngology - head and neck surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05015530 (Assessment of Sino-nasal Microbial Communities Changes in Adult Patients With Chronic Rhinosinusitis by 16 rRNA Gene Amplicon Sequencing Before and After 1-month Treatment Duration With Healsea® Chronic), which is not on this map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Assessment of Sino-nasal Microbial Communities Changes in Adult Patients With Chronic Rhinosinusitis by 16 rRNA Gene Amplicon Sequencing Before and After 1-month Treatment Duration With Healsea® Chronic: an Exploratory Study
Who cites it
20 citing papers in PubMed, 52 citations in OpenAlex.
- Quantitative PCR-Based Analysis of Bacterial Profiles in Periapical Lesions and Maxillary Sinus in Odontogenic Sinusitis.International journal of molecular sciences · 2026Article
- Implant rehabilitation of extensive maxillary bone loss secondary to chronic odontogenic sinusitis using a press-fit autogenous ramal block graft: a multidisciplinary staged approach.Journal of the Korean Association of Oral and Maxillofacial Surgeons · 2026Article
- Microbiological Comparison of Maxillary Sinus Rinses in Non-Odontogenic and Odontogenic Sinusitis of Primarily Endodontic Origin.Journal of clinical medicine · 2025Article
- Investigating the Role of the Sinus Microbiome and Cytokine Profile in the SNOT-22 Response After Functional Endoscopic Sinus Surgery in Chronic Rhinosinusitis Patients.Journal of clinical medicine · 2025Article
- Microbiota transplantation.Heliyon · 2024Review
- Chronic Rhinosinusitis-Microbiological Etiology, Potential Genetic Markers, and Diagnosis.International journal of molecular sciences · 2024Review
- Nasal Microbiota and Sensitivity Pattern in Rhinosinusitis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024Article
- Hyaluronic Acid in Rhinology: Its Uses, Advantages and Drawbacks-A Review.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023Article
- The difference in pathogenic bacteria between chronic rhinosinusitis in patients with and without Sjogren's syndrome: a retrospective case-control study.BMC infectious diseases · 2022Article
- The Role of Probiotics in Chronic Rhinosinusitis Treatment: An Update of the Current Literature.Healthcare (Basel, Switzerland) · 2021Review
- Chronic Diseases Associated withJournal of fungi (Basel, Switzerland) · 2021Review
- Influence of the Microbiome on Chronic Rhinosinusitis With and Without Polyps: An Evolving Discussion.Frontiers in allergy · 2021Review
- Clinical Detection of Chronic Rhinosinusitis through Next-Generation Sequencing of the Oral Microbiota.Microorganisms · 2020Article
- Association between the sinus microbiota with eosinophilic inflammation and prognosis in chronic rhinosinusitis with nasal polyps.Experimental & molecular medicine · 2020Article
- The Microbiome and Chronic Rhinosinusitis.Immunology and allergy clinics of North America · 2020Review
- Article
- Article
- Predictors of nasal bacterial culture rates in patients with chronic rhinosinusitis.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2020Article
- Recent Trends in Bacteriology of Adult Patients with Chronic Rhinosinusitis.Journal of clinical medicine · 2019Article
- Current Understanding of the Acute Exacerbation of Chronic Rhinosinusitis.Frontiers in cellular and infection microbiology · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chronic rhinosinusitis (CRS) is a multifactorial condition in which the microbiota plays a pathogenic role. The nature of the interaction between the microbiota and the local immune system is very complex and has not been fully elucidated. Recent improvements in the microbiological techniques have greatly advanced our understanding of the complex nature of this interaction. This paper summarizes the current state of the rapidly evolving research on this subject. Defining the nature of the role of the microbiota in CRS is important because of the associated therapeutic implications.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.