Evidence map›Paper›PMID 30506051›Full record

ReviewWorld journal of otorhinolaryngology - head and neck surgery2018

Acquired cystic fibrosis transmembrane conductance regulator dysfunction.

Catherine Banks, Laura Freeman, Do Yeon Cho, Bradford A Woodworth

Abstract readReview
In one paragraph

Review in World journal of otorhinolaryngology - head and neck surgery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Article
  3. Lipopolysaccharide Causes Acquired CFTR Dysfunction in Murine Nasal Airways.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
  4. Article
  5. Article
  6. Article
  7. Red ginseng aqueous extract improves mucociliary transport dysfunction and histopathology in CF rat airways.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Antibiotic eluting sinus stents.Laryngoscope investigative otolaryngology · 2020
    Review
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Catherine BanksDepartment of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Laura FreemanDepartment of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Do Yeon ChoDepartment of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.
Bradford A WoodworthDepartment of Otolaryngology Head & Neck Surgery, University of Alabama at Birmingham, Birmingham, AL, USA.

Funding

UAB CF Research and Translation Core CenterP30DK072482 · NIDDK · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI David M. Bedwell · 2007 to 2026
$23.0M
Ivacaftor for Acquired CFTR Dysfunction in Chronic RhinosinusitisR01HL133006 · NHLBI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WOODWORTH, BRADFORD ALAN · 2016 to 2020
$1.7M
NHLBI NIH HHS R01 HL133006NIDDK NIH HHS P30 DK072482
6 · The paper itself

Abstract

Sinonasal respiratory epithelium is a highly regulated barrier that employs mucociliary clearance (MCC) as the airways first line of defense. The biological properties of the airway surface liquid (ASL), combined with coordinated ciliary beating, are critical components of the mucociliary apparatus. The ASL volume and viscosity is modulated, in part, by the cystic fibrosis transmembrane conductance regulator (CFTR). The CFTR is an anion transporter of chloride (Cl

Indexed as

CFTRCFTR deficiencyCFTR dysfunctionChronic obstructive pulmonary diseaseChronic rhinosinusitisChronic sinusitisCystic fibrosisHypoxial-ascorbateResveratrolTobacco

Identifiers

PMID30506051
PMCPMC6251951

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.