Evidence map›Paper›PMID 30505947›Full record

ArticlemSystems

Genome-Wide Analysis of Transcriptional Changes and Genes That Contribute to Fitness during Degradation of the Anthropogenic Pollutant Pentachlorophenol by Sphingobium chlorophenolicum.

Jake J Flood, Shelley D Copley

Open access · goldAbstract read
In one paragraph

Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Jake J FloodDepartment of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA.
Shelley D CopleyDepartment of Molecular, Cellular and Developmental Biology, University of Colorado Boulder, Boulder, Colorado, USA.
University of Colorado Boulder · US

Funding

Elucidation and Evolutionary Potential of a Latent Pathway for PLP SynthesisR01GM083285 · NIGMS · UNIVERSITY OF COLORADO · PI COPLEY, SHELLEY D. · 2008 to 2016
$2.3M
NIGMS NIH HHS R01 GM083285
6 · The paper itself

Abstract

Pentachlorophenol (PCP) is a highly toxic pesticide that was first introduced in the 1930s. The alphaproteobacterium Sphingobium chlorophenolicum, which was isolated from PCP-contaminated sediment, has assembled a metabolic pathway capable of completely degrading PCP. This pathway produces four toxic intermediates, including a chlorinated benzoquinone that is a potent alkylating agent and three chlorinated hydroquinones that react with O

Indexed as

benzoquinonebiodegradationhydroquinonepentachlorophenolRNA-seqSphingobium chlorophenolicumTn-seq

Identifiers

PMID30505947
PMCPMC6247019
OpenAlexW2900770371

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.