ArticlemSystems
Metatranscriptomic and Thermodynamic Insights into Medium-Chain Fatty Acid Production Using an Anaerobic Microbiome.
Article in mSystems. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
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Who cites it
42 citing papers in PubMed, 92 citations in OpenAlex.
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- Metagenome-assembled genomes from microbiomes fermenting dairy coproducts.Microbiology resource announcements · 2024Article
- Non-invasive VOCs detection to monitor the gut microbiota metabolism in-vitro.Scientific reports · 2024Article
- Two-stage conversion of syngas and pyrolysis aqueous condensate into L-malate.Biotechnology for biofuels and bioproducts · 2024Article
- Medium-chain carboxylates production from plant waste: kinetic study and effect of an enriched microbiome.Biotechnology for biofuels and bioproducts · 2024Article
- Refinement of the "mSystems · 2024Article
- Evaluating the feasibility of medium-chain oleochemical synthesis using microbial chain elongation.Journal of industrial microbiology & biotechnology · 2024Article
- Energy and nutrient recovery from municipal and industrial waste and wastewater-a perspective.Journal of industrial microbiology & biotechnology · 2024Review
- Targeted rRNA depletion enables efficient mRNA sequencing in diverse bacterial species and complex co-cultures.mSystems · 2023Article
- Trophic interactions shape the spatial organization of medium-chain carboxylic acid producing granular biofilm communities.The ISME journal · 2023Article
- Dietary β-hydroxybutyric acid improves the growth performance of young ruminants based on rumen microbiota and volatile fatty acid biosynthesis.Frontiers in microbiology · 2023Article
- Why do lactic acid bacteria thrive in chain elongation microbiomes?Frontiers in bioengineering and biotechnology · 2023Article
- A metagenome-level analysis of a microbial community fermenting ultra-filtered milk permeate.Frontiers in bioengineering and biotechnology · 2023Article
- Comparison of metagenomes from fermentation of various agroindustrial residues suggests a common model of community organization.Frontiers in bioengineering and biotechnology · 2023Article
- Revealing the Characteristics of Glucose- and Lactate-Based Chain Elongation for Caproate Production bymSystems · 2022Article
- The PROVIT Study-Effects of Multispecies Probiotic Add-on Treatment on Metabolomics in Major Depressive Disorder-A Randomized, Placebo-Controlled Trial.Metabolites · 2022Article
- Metagenome-Assembled Genomes from a Microbiome Grown in Dairy Manure Hydrolysate.Microbiology resource announcements · 2022Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biomanufacturing from renewable feedstocks can offset fossil fuel-based chemical production. One potential biomanufacturing strategy is production of medium-chain fatty acids (MCFA) from organic feedstocks using either pure cultures or microbiomes. While the set of microbes in a microbiome can often metabolize organic materials of greater diversity than a single species can and while the role of specific species may be known, knowledge of the carbon and energy flow within and between organisms in MCFA-producing microbiomes is only now starting to emerge. Here, we integrated metagenomic, metatranscriptomic, and thermodynamic analyses to predict and characterize the metabolic network of an anaerobic microbiome producing MCFA from organic matter derived from lignocellulosic ethanol fermentation conversion residue. A total of 37 high-quality (>80% complete, <10% contamination) metagenome-assembled genomes (MAGs) were recovered from the microbiome, and metabolic reconstruction of the 10 most abundant MAGs was performed. Metabolic reconstruction combined with metatranscriptomic analysis predicted that organisms affiliated with
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.