ArticleAlzheimer's & dementia (Amsterdam, Netherlands)2018
Utility of the NIH Toolbox for assessment of prodromal Alzheimer's disease and dementia.
Article in Alzheimer's & dementia (Amsterdam, Netherlands), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 2 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
40 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- A Systematic Review and Meta-Analysis of the Use of the National Institutes of Health Toolbox Cognition Battery in Clinical Populations.Neuropsychology review · 2026Pooled it
- Psychometric properties of the NIH Toolbox Cognition Battery composites in older adults at risk for Alzheimer's disease and related dementias: A systematic review.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Pooled it
- Utility of the iPad NIH Toolbox Cognition Battery in a clinical trial of older adults.Journal of the American Geriatrics Society · 2021Trial
- Neuroimaging Correlates of the NIH Toolbox Cognition and Trail Making Tests: Normative Benchmarks in Healthy Aging.Clinical and translational neuroscience · 2026Article
- Exploring the link between National Institutes of Health (NIH) Toolbox Cognition Battery performance and everyday functioning in mild cognitive impairment.Neuropsychology · 2026Article
- NIH Toolbox Cognition Performance in Older Adults with Normal Cognition, Mild Cognitive Impairment, and Mild Dementia of the Alzheimer's Type: Results from the ARMADA Study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2025Article
- Cross-domain latent profiles of MCI and dementia are most differentiated by social and emotional functioning.Journal of the International Neuropsychological Society : JINS · 2025Article
- Evaluating the factor structure and construct validity of the NIH toolbox in older adults, with a focus on cognitive normalcy and amnestic mild cognitive impairment: considerations for diversity, including insights from persons over 85 years of age and Black older Americans.Journal of the International Neuropsychological Society : JINS · 2025Article
- The validity of studying healthy aging with cognitive tests measuring different constructs.Scientific reports · 2024Article
- Development and Validation of a Vocabulary Measure in the Mobile Toolbox.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Article
- Identification of amnestic mild cognitive impairment among Black and White community-dwelling older adults using NIH Toolbox Cognition tablet battery.Journal of the International Neuropsychological Society : JINS · 2024Article
- Neurovascular coupling, functional connectivity, and cerebrovascular endothelial extracellular vesicles as biomarkers of mild cognitive impairment.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024Article
- Measuring Multidimensional Aspects of Health in the Oldest Old Using the NIH Toolbox: Results From the ARMADA Study.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2024Article
- Exploring symptom clusters in mild cognitive impairment and dementia with the NIH Toolbox.Journal of the International Neuropsychological Society : JINS · 2024Article
- Utility of the NIH Toolbox Cognition Battery in middle to older aged adults with longstanding type 1 diabetes: The DCCT/EDIC study.The Clinical neuropsychologist · 2024Article
- Protocol for a single-arm, pilot trial of creatine monohydrate supplementation in patients with Alzheimer's disease.Pilot and feasibility studies · 2024Article
- Construct validation of NIH Toolbox Cognition Battery premorbid cognitive functioning scores in Black and White older Americans with and without mild cognitive impairment.Journal of the International Neuropsychological Society : JINS · 2024Article
- Psychometric properties of the NIH Toolbox Cognition and Emotion Batteries among children and adolescents with congenital heart defects.Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence · 2024Article
- Predicting Brain Amyloid Status Using the National Institute of Health Toolbox (NIHTB) for Assessment of Neurological and Behavioral Function.The journal of prevention of Alzheimer's disease · 2024Article
- Design and Harmonization Approach for the Multi-Institutional Neurocognitive Discovery Study (MINDS) of Adult Congenital Heart Disease (ACHD) Neuroimaging Ancillary Study: A Technical Note.Journal of cardiovascular development and disease · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
introductionThe NIH Toolbox Cognition Battery (NIHTB-CB) is a computer-based protocol not yet validated for clinical assessment.
methodsWe administered the NIHTB-CB and traditional neuropsychological tests to 247 Memory Disorders and Alzheimer's Prevention Clinic patients with subjective cognitive decline, mild cognitive impairment, mild dementia due to Alzheimer's disease, and normal cognition. Principal component analysis, partial correlations, and univariate general linear model tests were performed to assess construct validity. Discriminant function analyses compared classification accuracy.
resultsPrincipal component analysis identified three conceptually coherent factors: memory (MEM DISCUSSION: The NIHTB-CB is a valid method to assess neurocognitive domains pertinent to aging and dementia and has utility for applications in a memory clinic setting.
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