ArticleAnnals of surgical treatment and research2018
Analysis of prognostic factors affecting poor outcomes in 41 cases of Fournier gangrene.
Article in Annals of surgical treatment and research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.
- Necrotising Fasciitis in Patients With Diabetes: A Systematic Review of Mortality-Associated Clinical Factors.International wound journal · 2026Pooled it
- The role of negative-pressure wound therapy in Fournier's gangrene: Association with mortality.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2026Article
- Clinical and laboratory predictors of mortality in Fournier's gangrene: prognostic role of the HALP score.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026Article
- Fournier's Gangrene Mortality Index (FGMI): A New Scoring System for Predicting Fournier's Gangrene Mortality.Diagnostics (Basel, Switzerland) · 2024Article
- Comparative analysis of scoring systems for predicting mortality in Fournier gangrene: single center, 15 years experience.Updates in surgery · 2024Article
- Prognostic factors and clinical outcomes in Fournier's Gangrene: a retrospective study of 35 patients.BMC infectious diseases · 2024Article
- Fournier's Gangrene Surgical Reconstruction: A Systematic Review.Journal of clinical medicine · 2024Review
- Comprehensive management and outcomes in female patients with Fournier's gangrene: A case report.SAGE open medical case reports · 2024Article
- The role of C-reactive protein albumin ratio for predicting mortality in patients with Fournier's gangrene.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2023Article
- Can HALP score, a new prognostic tool, take the place of traditional scoring systems in Fournier's gangrene?International urology and nephrology · 2023Article
- The importance of the scoring system in Fournier's gangrene.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Risk factors for mortality in Fournier's gangrene of anorectal origin.Ulusal travma ve acil cerrahi dergisi = Turkish journal of trauma & emergency surgery : TJTES · 2022Article
- Management of Fournier's gangrene during the Covid-19 pandemic era: make a virtue out of necessity.Basic and clinical andrology · 2022Article
- Practical Review of the Current Management of Fournier's Gangrene.Plastic and reconstructive surgery. Global open · 2022Review
- Impact of radiological diagnostics in the survivor of disseminated Fournier gangrene patient with septic pulmonary embolism.BMJ case reports · 2019Article
- Fournier's Gangrene and Intravenous Drug Abuse: an Unusual Case Report and Review of The Literature.Open medicine (Warsaw, Poland) · 2019Article
- Severe bacterial skin infections.Anais brasileiros de dermatologiaArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeWe present our experience involving the management of this disease, identifying prognostic factors affecting treatment outcomes.
methodsThe patients treated for Fournier gangrene at our institution were retrospectively reviewed. Data collected included demographics, extent of soft tissue necrosis, predisposing factors, etiological factors, laboratory values, and treatment outcomes. The severity index and score were calculated. Multivariate regression analysis was used to determine the association between potential predictors and clinical outcomes.
resultsA total of 41 patients (male:female = 33:8) were studied. The mean age was 54.4 years (range, 24-79 years). The most common predisposing factor was diabetes mellitus (n = 19, 46.3%). Sixteen patients (39.0%) were current smokers. Seven patients had chronic kidney disease. The most frequent etiology was urogenital lesion (41.5%). The mortality rate was 22.0% (n = 9). Multivariate regression analyses showed that extension of necrosis beyond perineal/inguinal area and pre-existing chronic kidney disease were significant and independent predictors of mortality. Extension of necrosis beyond perineal/inguinal area was a significant predictor of increased duration in the intensive care unit and hospital stay. In addition, pre-existing chronic kidney disease was a significant predictor of flap reconstruction in the wound.
conclusionFournier gangrene with extensive soft tissue necrosis and pre-existing chronic kidney disease was associated with poor prognosis and complexity of patient management. Early recognition of dissemination and premorbid renal function is essential to reduce mortality and establish a management plan for this disease.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.