Evidence map›Paper›PMID 30505732›Full record

ReviewTranslational andrology and urology2018

Sexual dysfunction and infertility in the male spina bifida patient.

Nanfu Deng, Nannan Thirumavalavan, Jonathan A Beilan, Alexander J Tatem, Mark S Hockenberry, Alexander W Pastuszak, Larry I Lipshultz

Open access · hybridAbstract readReview
In one paragraph

Review in Translational andrology and urology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Review
  3. Reproductive Education and Sexual Abuse Among Individuals With Spina Bifida: A Mixed Methods Study.Archives of rehabilitation research and clinical translation · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. What has changed in pediatric neurosurgical care in spina bifida? A 30-year UAB/Children's of Alabama observational overview.Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery · 2023
    Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Perspectives on urological care in spina bifida patients.Intractable & rare diseases research · 2021
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Nanfu DengBaylor College of Medicine, Houston, TX, USA.
Nannan ThirumavalavanCenter for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA.
Jonathan A BeilanScott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
Alexander J TatemScott Department of Urology, Baylor College of Medicine, Houston, TX, USA.
Mark S HockenberryCenter for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA.
Alexander W PastuszakCenter for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA.
Larry I LipshultzCenter for Reproductive Medicine, Baylor College of Medicine, Houston, TX, USA.
Baylor College of Medicine · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spina bifida is a congenital neural tube defect with many neurological implications, as well as decreased sexual function and infertility. Few studies have directly investigated infertility in men with spina bifida. Infertility in this special patient population is primarily the result of spermatogenic defects and/or failure of sperm transport due to erectile or ejaculatory dysfunction. The severity of sexual and reproductive dysfunction seems to correlate with higher level of spina cord lesion and presence of hydrocephalus. Phosphodiesterase 5 inhibitors (PDE5is) have been shown to be effective for erectile dysfunction in some men with spina bifida. Surgical sperm retrieval from the genitourinary tract and rectal probe electroejaculation can serve as methods for collecting sperm from those with ejaculatory dysfunction or retrograde ejaculation. Assisted reproductive technology such as intracytoplasmic sperm injection allows isolated sperm from men with infertility to achieve fertilization. Since most spina bifida patients are surviving into adolescence and adulthood due to improved medical and surgical advancements, it is paramount for healthcare professionals to address issues related their sexual and reproductive function.

Indexed as

erectile dysfunctionmale infertilityspermatogenesisSpina bifida

Identifiers

PMID30505732
PMCPMC6256049
OpenAlexW2898604263

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.