Evidence map›Paper›PMID 30505650›Full record

ArticleJournal of Biomedicine (Sydney, NSW)2018

Muscle and Bone Mass Loss in the Elderly Population: Advances in diagnosis and treatment.

Carlos J Padilla Colón, Irma L Molina-Vicenty, María Frontera-Rodríguez, Alejandra García-Ferré, Bernabejoel Ponce Rivera, Gerardo Cintrón-Vélez, Sebastián Frontera-Rodríguez

Abstract read
In one paragraph

Article in Journal of Biomedicine (Sydney, NSW), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

68 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
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  7. Article
  8. Article
  9. Review
  10. The Impact of Ageing on Fibrillar Collagens.Sub-cellular biochemistry · 2026
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Association Between Prehip Fracture Antidepressant Use and Posthip Fracture Length of Hospital Stay in Medicare Beneficiaries and Assessing Sex Differences.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2025
    Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article

8 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Carlos J Padilla ColónDepartment of Education, Physical Education and Health Programs, San Juan, PR, USA.
Irma L Molina-VicentyResearch and Development Service (151), VA Caribbean Healthcare System, San Juan PR, USA.
María Frontera-RodríguezResearch and Development Service (151), VA Caribbean Healthcare System, San Juan PR, USA.
Alejandra García-FerréResearch and Development Service (151), VA Caribbean Healthcare System, San Juan PR, USA.
Bernabejoel Ponce RiveraDepartment of Biology, University of Puerto Rico, Mayaguez Campus, Mayaguez, PR, USA.
Gerardo Cintrón-VélezResearch and Development Service (151), VA Caribbean Healthcare System, San Juan PR, USA.
Sebastián Frontera-RodríguezResearch and Development Service (151), VA Caribbean Healthcare System, San Juan PR, USA.

Funding

TECHNOLOGIES AND RESOURCES FOR CORE LABORATORIESU54MD007587 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI LUCIANO, CARLOS A., WOJNA, VALERIE · 2012 to 2018
$23.2M
NIMHD NIH HHS U54 MD007587
6 · The paper itself

Abstract

Aging is the result of different functional changes leading to a substantial reduction of all human capabilities. A variety of anatomical and physiological changes occur with advancing age. These changes are more evident in the elderly population. There are various methods to measure muscle and bone mass loss, but the dual X-ray absorptiometry (DXA) is considered one of the most efficient. The elderly population (65 years and older) has been increasing throughout the years. Loss of muscle mass (sarcopenia) and loss bone mass (osteopenia or osteoporosis) with advancing age, when untreated, represent a major public health problem for the elderly population and may result in loss of independence in later life. Untreated age-related sarcopenia and osteopenia/osteoporosis increase the risk for falls and fractures, making older individuals more susceptible to the development of mobility limitations or severe disabilities that ultimately affect their capacity for independence. In this review, we will discuss the muscle and bone mass loss in the elderly population and advances in diagnosis and treatment.

Indexed as

OsteopeniaOsteoporosisSarcopenia

Identifiers

PMID30505650
PMCPMC6261527

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.