Evidence map›Paper›PMID 30505583›Full record

ArticleJournal of gastrointestinal oncology2018

Using the Albumin-Bilirubin (ALBI) grade as a prognostic marker for radioembolization of hepatocellular carcinoma.

Homan Mohammadi, Yazan Abuodeh, William Jin, Jessica Frakes, Mark Friedman, Benjamin Biebel, Junsung Choi, Ghassan El-Haddad, Bela Kis, Jennifer Sweeney and 1 more

Abstract read
In one paragraph

Article in Journal of gastrointestinal oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Homan MohammadiDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Yazan AbuodehDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.
William JinMorsani College of Medicine, University of South Florida, Tampa, FL, USA.
Jessica FrakesDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Mark FriedmanDepartment of Gastroenterology, Moffitt Cancer Center, Tampa, FL, USA.
Benjamin BiebelDepartment of Gastroenterology, Moffitt Cancer Center, Tampa, FL, USA.
Junsung ChoiDepartment of Gastroenterology, Moffitt Cancer Center, Tampa, FL, USA.
Ghassan El-HaddadDepartment of Gastroenterology, Moffitt Cancer Center, Tampa, FL, USA.
Bela KisDepartment of Gastroenterology, Moffitt Cancer Center, Tampa, FL, USA.
Jennifer SweeneyDepartment of Gastroenterology, Moffitt Cancer Center, Tampa, FL, USA.
Sarah HoffeDepartment of Radiation Oncology, Moffitt Cancer Center, Tampa, FL, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe Child-Pugh (CP) class is a commonly used scoring system to measure liver function in patients with hepatocellular carcinoma (HCC). We correlate the Albumin-Bilirubin (ALBI) grading system and CP to overall survival in our HCC patients receiving radioembolization.

methodsWe retrospectively evaluated patients who received radioembolization for HCC between the years 2009-2014. We evaluated the albumin and bilirubin levels in our patients prior to receiving their first (n=124) radioembolization. The ALBI grades were calculated from these data with the formula (log

resultsMedian survival differences between CP class A and B and between ALBI grade 1 and 2 were 4.7 and 9.9 months, respectively. A subset of ALBI grades 1 and 2 were identified within our CP class A patients with a median survival difference of 9.9 months.

conclusionsALBI is a more sensitive marker of liver function than CP in the setting of mild dysfunction. Using ALBI, we identified a subset of patients that have significantly better outcomes from Y-90 radioembolization than previously identified with CP.

Indexed as

Albumin-bilirubin (ALBI)Child-Pugh (CP)Hepatocellular carcinoma (HCC)radioembolization

Identifiers

PMID30505583
PMCPMC6219966

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.