Evidence map›Paper›PMID 30505377›Full record

ArticleJournal of atrial fibrillation2018

Atrial Fibrillation and Objective Sleep Quality by Slow Wave Sleep.

Younghoon Kwon, Sneha Gadi, Neil R Shah, Christopher Stout, Jacob N Blackwell, Yeilim Cho, Ryan J Koene, Nishaki Mehta, Sula Mazimba, Andrew E Darby and 2 more

Abstract read
In one paragraph

Article in Journal of atrial fibrillation, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Obstructive Sleep Apnea and Atrial Fibrillation.Journal of clinical medicine · 2022
    Review
  6. Sleep time and efficiency in patients undergoing laboratory-based polysomnography.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
  7. Visit-to-visit blood pressure variability and sleep architecture.Journal of clinical hypertension (Greenwich, Conn.) · 2021
    Article
  8. Article
  9. Sleep Apnea and Heart.Sleep medicine research · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Younghoon KwonCardiovascular Division, Department of Medicine, University of Virginia.
Sneha GadiCardiovascular Division, Department of Medicine, University of Virginia.
Neil R ShahCardiovascular Division, Department of Medicine, University of Virginia.
Christopher StoutCardiovascular Division, Department of Medicine, University of Virginia.
Jacob N BlackwellCardiovascular Division, Department of Medicine, University of Virginia.
Yeilim ChoCardiovascular Division, Department of Medicine, University of Virginia.
Ryan J KoeneDepartment of Cardiovascular Medicine, Electrophysiology Section, Cleveland Clinic Foundation.
Nishaki MehtaCardiovascular Division, Department of Medicine, University of Virginia.
Sula MazimbaCardiovascular Division, Department of Medicine, University of Virginia.
Andrew E DarbyCardiovascular Division, Department of Medicine, University of Virginia.
John D FergusonCardiovascular Division, Department of Medicine, University of Virginia.
Kenneth C BilchickCardiovascular Division, Department of Medicine, University of Virginia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSelf-reported poor sleep quality has been suggested in patients with AF. Slow wave sleep (SWS) is considered the most restorative sleep stage and represents an important objective measure of sleep quality. The aim of this study was to compare quantity of SWS between patients with and without AF. METHODS AND

resultsWe included patients with and without a documented history of AF by reviewing clinically indicated polysomnography data from a single sleep center. Patients on medications with potential influence on sleep architecture were excluded. Logistic regression was performed to determine the association between AF and SWS time (low vs. high) adjusting for age, gender, body mass index, and sleep apnea. In a 2:1 case-control set-up, a total of 205 subjects (139 with AF, 66 without AF) were included. Mean age was 62 (SD: 14.3) years and 59% were men. Patients with AF had lower SWS time (11.1 vs. 16.6 min, p=0.02). In multivariable analysis, prevalent AF was associated with low SWS independent of sleep apnea and other potential confounders (OR 2.5 [1.3, 5.0], p=0.006). Limiting the analysis to patients whose total sleep time was greater than 4 hours (by excluding N=31) resulted in more robust results (OR 3.9 [1.7, 9.7]. p=0.002).

conclusionAF is associated with more impaired sleep quality as indicated by lower quantity of SWS. More studies are needed to explore the mechanistic interactions between AF and sleep.

Indexed as

Atrial FibrillationSleep ApneaSlow Wave Sleep

Identifiers

PMID30505377
PMCPMC6244306

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.