ArticleThe open dentistry journal2018
Effectiveness of S-PRG Filler-Containing Toothpaste in Inhibiting Demineralization of Human Tooth Surface.
Article in The open dentistry journal, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
15 citing papers in PubMed.
- Biological Effects on S-PRG: An Integrative Review.Journal of functional biomaterials · 2026Review
- Bioactivity and potential applications of surface pre-reacted glass-ionomer (S-PRG) filler-containing dental materials for geriatric oral health: A scoping review.The Japanese dental science review · 2025Review
- Article
- Effect of polishing systems on the roughness, color, and staining of conventional and bulk-fill resin composites with and without S-PRG filler.Clinical oral investigations · 2025Article
- Technological dental sealants: in vitro evaluation of material properties and antibiofilm potential.BMC oral health · 2025Article
- Occlusion, acid resistance, and elemental characterization of dentin treated with desensitizing agents.Brazilian oral research · 2025Article
- Salivary fluoride concentrations following toothbrushing with experimental toothpaste containing surface pre-reacted glass-ionomer (S-PRG) filler.Clinical oral investigations · 2023Article
- Multiple-Ion Releasing Bioactive Surface Pre-Reacted Glass-Ionomer (S-PRG) Filler: Innovative Technology for Dental Treatment and Care.Journal of functional biomaterials · 2023Review
- Dentin anti-demineralization potential of surface reaction-type pre-reacted glass-ionomer filler containing self-adhesive resin cement.Clinical oral investigations · 2022Article
- S-PRG-based toothpastes compared to NaF toothpaste and NaF varnish on dentin permeability in vitro.Journal of applied oral science : revista FOB · 2022Article
- Interactions of boron released from surface pre-reacted glass ionomer with enamel/dentin and its effect on pH.Scientific reports · 2021Article
- Antibacterial coating of tooth surface with ion-releasing pre-reacted glass-ionomer (S-PRG) nanofillers.Heliyon · 2021Article
- The Potential of Hydroxyapatite Toothpaste to Prevent Root Caries: A pH-Cycling Study.Clinical, cosmetic and investigational dentistry · 2021Article
- Efficacy of S-PRG filler containing varnishes on enamel demineralization prevention.Scientific reports · 2020Article
- Comparison of hydroxyapatite and fluoride oral care gels for remineralization of initial caries: a pH-cycling study.BDJ open · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesUsing an established pH-cycling caries model, the authors evaluated the effectiveness of toothpastes containing Surface Pre-reacted Glass-ionomer filler (S-PRG) in preventing tooth surface demineralization. MATERIALS AND
methods210 tooth blocks were randomly assigned to seven experimental groups (30 blocks/group): no treatment (A), and toothpaste containing either NaF (B), 0 wt% S-PRG (C), 1 wt% S-PRG (D), 5 wt% S-PRG (E), 20 wt% S-PRG (F) or 30 wt% S-PRG (G). Groups were subjected to 14-day demineralization for development of early caries lesions using a pH-cycling caries model. Demineralization was assessed using Quantitative Light-induced Fluorescence (QLF) and Transverse Microradiography (TMR). All pairwise contrasts (between treatments) were tested using Analysis of Variance (ANOVA), and then Tukey's HSD for multiple comparisons. All
resultsWith QLF, there was a significant (ANOVA;
conclusionToothpaste containing S-PRG filler can serve as an effective caries control tool. S-PRG filler-containing dentifrice to be more effective in preventing tooth demineralization than 1100 ppm fluoride provided as sodium fluoride.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.