Evidence map›Paper›PMID 30505336›Full record

ArticleNutrition & metabolism2018

Cristiane Freitas Rodrigues, Willian Salgueiro, Matheus Bianchini, Juliana Cristina Veit, Robson Luiz Puntel, Tatiana Emanuelli, Cristiane Casagrande Dernadin, Daiana Silva Ávila

Open access · goldAbstract read
In one paragraph

Article in Nutrition & metabolism, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Cristiane Freitas Rodrigues1UNIPAMPA-Programa de Pós-Graduação em Bioquímica, Universidade Federal do Pampa, BR 472 - Km 592, Caixa Postal 118, Uruguaiana, RS CEP 97500-970 Brazil.
Willian Salgueiro1UNIPAMPA-Programa de Pós-Graduação em Bioquímica, Universidade Federal do Pampa, BR 472 - Km 592, Caixa Postal 118, Uruguaiana, RS CEP 97500-970 Brazil.
Matheus Bianchini1UNIPAMPA-Programa de Pós-Graduação em Bioquímica, Universidade Federal do Pampa, BR 472 - Km 592, Caixa Postal 118, Uruguaiana, RS CEP 97500-970 Brazil.
Juliana Cristina Veit2Departamento de Tecnologia e Ciência de Alimentos, Universidade Federal de Santa Maria, Centro de Ciências Rurais, Santa Maria, Rio Grande do Sul Brazil.
Robson Luiz Puntel1UNIPAMPA-Programa de Pós-Graduação em Bioquímica, Universidade Federal do Pampa, BR 472 - Km 592, Caixa Postal 118, Uruguaiana, RS CEP 97500-970 Brazil.
Tatiana Emanuelli2Departamento de Tecnologia e Ciência de Alimentos, Universidade Federal de Santa Maria, Centro de Ciências Rurais, Santa Maria, Rio Grande do Sul Brazil.
Cristiane Casagrande Dernadin1UNIPAMPA-Programa de Pós-Graduação em Bioquímica, Universidade Federal do Pampa, BR 472 - Km 592, Caixa Postal 118, Uruguaiana, RS CEP 97500-970 Brazil.
Daiana Silva Ávila1UNIPAMPA-Programa de Pós-Graduação em Bioquímica, Universidade Federal do Pampa, BR 472 - Km 592, Caixa Postal 118, Uruguaiana, RS CEP 97500-970 Brazil.ORCID 0000-0002-8673-1909
Universidade Federal do Pampa · BRUniversidade Federal de Santa Maria · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background

methodsWe prepared hexane (HE) and Bligh-Dyer (BDE) extracts, evaluated and compared their safety, antioxidant potential and their lipid-lowering activity in the worms.

resultsThe characterization of both extracts demonstrated that there were no differences in their lipid composition; however, BDE depicted better antioxidant potential. Both extracts reduced worm's survival from 2%, and reproduction was reduced following treatment with both extracts, though a more notable effect was observed in HE-treated worms. In addition, the non-toxic concentration of both extracts (1%) increased stress resistance against paraquat toxicity in an antidote paradigm. Notably, this same concentration of both extracts reduced lipid accumulation in obese worms, which was not caused by food deprivation.

conclusionsTaken together, our data demonstrate that both extraction methods from chia seeds result in oils that are rich in mono and polyunsaturated fatty acids, which may modulate lipid accumulation and provide antioxidant resistance in

Indexed as

AntioxidantC. elegansLipidsSalvia hispanica and chia

Identifiers

PMID30505336
PMCPMC6260566
OpenAlexW2902409902

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.